Department of Surgery, Imo State University Teaching Hospital, Orlu, Imo State, Nigeria.
World J Surg Oncol. 2010 Aug 25;8:73. doi: 10.1186/1477-7819-8-73.
Albinism is a genetic disorder characterized by lack of skin pigmentation. It has a worldwide distribution but is commoner in areas close to the equator like Nigeria. Skin cancers are a major risk associated with albinism and are thought to be a major cause of death in African albinos. Challenges faced in the care of these patients need to be highlighted in order to develop a holistic management approach with a significant public health impact. The aim of the study was to determine the pattern of skin cancers seen in Albinos, and to highlight problems encountered in their management.
Case records of albinos managed in Imo state University teaching Hospital from June 2007 to May 2009 were reviewed. The data obtained was analyzed using descriptive statistics.
In the period under review, albinos accounted for 67% of patients managed for primary skin cancers. There were twenty patients with thirty eight (38) lesions. Sixty one percent of the patients were below 40 years. Average duration of symptoms at presentation was 26 months. The commonest reason for late presentation was the lack of funds. Squamous cell carcinoma was the commonest histologic variant. Most patients were unable to complete treatment due to lack of funds.
Albinism appears to be the most important risk factor in the development of skin cancers in our environment. Late presentation and poor rate of completion of treatment due to poverty are major challenges.
白化病是一种遗传疾病,其特征是缺乏皮肤色素沉着。它在世界各地都有分布,但在靠近赤道的地区如尼日利亚更为常见。皮肤癌是白化病的主要风险之一,被认为是非洲白化病患者死亡的主要原因。为了制定具有重大公共卫生影响的整体管理方法,需要强调这些患者面临的护理挑战。本研究的目的是确定白化病患者中皮肤癌的模式,并强调其管理中遇到的问题。
回顾了 2007 年 6 月至 2009 年 5 月在伊莫州立大学教学医院管理的白化病患者的病历。使用描述性统计分析获得的数据。
在审查期间,白化病患者占原发性皮肤癌患者的 67%。有二十名患者有三十八个(38)个病变。61%的患者年龄在 40 岁以下。就诊时症状的平均持续时间为 26 个月。延迟就诊的常见原因是缺乏资金。鳞状细胞癌是最常见的组织学变异。由于缺乏资金,大多数患者无法完成治疗。
在我们的环境中,白化病似乎是皮肤癌发展的最重要危险因素。由于贫困导致的晚期就诊和治疗完成率低是主要挑战。