一例先天性杆状肌病患者在生长激素治疗期间出现呼吸功能恶化。
Respiratory deterioration during growth hormone therapy in a case of congenital nemaline myopathy.
作者信息
Logghe K, Wit J M, Jennekens F, Pruijs J E
机构信息
Department of Paediatrics, University Hospital for Children and Youth, Het Wilhelmina Kinderziekenhuis, Utrecht, The Netherlands.
出版信息
Eur J Pediatr. 1990 Nov;150(1):69-71. doi: 10.1007/BF01959486.
PMID:2079082
Abstract
Congenital nemaline myopathy (CNM) is generally classified as a non-progressive or slowly progressive neuromuscular disease. We describe a boy with CNM and an isolated partial growth hormone (GH) deficiency. From the onset of GH therapy his respiratory capacity deteriorated rapidly. The possible association between this deterioration and GH therapy is discussed.
摘要
先天性线状体肌病（CNM）通常被归类为一种非进行性或缓慢进行性神经肌肉疾病。我们描述了一名患有CNM且伴有孤立性部分生长激素（GH）缺乏症的男孩。自开始生长激素治疗后，他的呼吸功能迅速恶化。本文讨论了这种恶化与生长激素治疗之间可能存在的关联。
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