Kimmey M B, Wang K Y, Haggitt R C, Mack L A, Silverstein F E
Department of Medicine, University of Washington School of Medicine, Seattle 98195.
Invest Radiol. 1990 Oct;25(10):1085-90. doi: 10.1097/00004424-199010000-00003.
Transabdominal ultrasound is frequently used to detect complications of inflammatory bowel disease. It has been proposed that ultrasound can distinguish between ulcerative colitis and Crohn's disease based on the degree of thickening and changes in the layered structure of the intestine. The authors evaluated the ability of ultrasound to distinguish between ulcerative colitis, Crohn's colitis, and normal colon by blindly comparing images made of resected colon specimens. The histologic interpretation of precisely the same area of tissue that was imaged was compared with the blinded image interpretation. Images from all 18 colitis specimens were correctly interpreted as being abnormal because of increased submucosal and overall wall thickness. Published ultrasound criteria for distinguishing between Crohn's disease and ulcerative colitis based on overall wall thickness and indistinctness of layers were inaccurate in 4 of 15 specimens and indeterminate in 3 cases. Ultrasound appears to be accurate in distinguishing normal from inflamed colon, but ultrasound findings alone should not be used to determine the cause of bowel inflammation.
经腹超声常用于检测炎症性肠病的并发症。有人提出，超声可根据肠壁增厚程度和肠壁分层结构变化来区分溃疡性结肠炎和克罗恩病。作者通过盲目比较切除的结肠标本图像，评估了超声区分溃疡性结肠炎、克罗恩结肠炎和正常结肠的能力。将成像的同一组织区域的组织学解释与盲法图像解释进行比较。所有18份结肠炎标本的图像均因黏膜下层和肠壁整体增厚而被正确解释为异常。已发表的基于肠壁整体厚度和层次不清来区分克罗恩病和溃疡性结肠炎的超声标准，在15份标本中有4份不准确，3例结果不确定。超声似乎能准确区分正常结肠和发炎结肠，但仅靠超声检查结果不应被用于确定肠道炎症的病因。
