Piconi C, Maccauro G, Muratori F, Brach Del Prever E
Department of Orthopaedics, Università Cattolica di Roma, Rome - Italy.
J Appl Biomater Biomech. 2003 Jan-Apr;1(1):19-32.
Ceramic biomaterials have gained widespread use in arthroprostheses joints. Ceramic oxides including alumina as á -corundum Al2 O3 and zirconia, as yttria-stabilised zirconia polycrystals, were used in large number of patients, especially in the manufacture of ball heads for hip replacements. The experience and the feedbacks gathered in more than 30-year clinical use of alumina, and 15-year use of zirconia are reviewed. The results of in vitro and in vivo studies on the biocompatibility of alumina and zirconia ceramics are analyzed as well as the studies on carcinogenicity. (Journal of Applied Biomaterials & Biomechanics 2003; 1: 19-32).
陶瓷生物材料已在关节置换假体中得到广泛应用。包括作为α-刚玉Al2O3的氧化铝和作为钇稳定氧化锆多晶体的氧化锆在内的陶瓷氧化物，已被大量应用于患者，尤其是用于制造髋关节置换的球头。本文综述了在氧化铝超过30年的临床应用以及氧化锆15年的临床应用中所积累的经验和反馈。分析了关于氧化铝和氧化锆陶瓷生物相容性的体外和体内研究结果以及致癌性研究结果。（《应用生物材料与生物力学杂志》2003年；1：19 - 32）
