Kidde Jason, Marcus Robin, Dibble Lee, Smith Sheldon, Lastayo Paul
Department of Physical Therapy, University of Utah, Salt Lake City, Utah, USA.
Physiother Can. 2009 Fall;61(4):197-209. doi: 10.3138/physio.61.4.197. Epub 2009 Nov 12.
To describe previously reported locomotor muscle and whole-body composition factors related to mobility in older individuals.
A narrative review of the literature, including a combination of search terms related to muscle and whole-body composition factors and to mobility in older individuals, was carried out. Statistical measures of association and risk were consolidated to summarize the common effects between studies.
Fifty-three studies were reviewed. Muscle and whole-body factors accounted for a substantial amount of the variability in walking speed, with coefficients of determination ranging from 0.30 to 0.47. Muscle power consistently accounted for a greater percentage of the variance in mobility than did strength. Risks associated with high fat mass presented a minimum odds ratio (OR) of 0.70 and a maximum OR of 4.07, while the minimum and maximum ORs associated with low lean mass were 0.87 and 2.30 respectively. Whole-body and regional fat deposits accounted for significant amounts of the variance in mobility.
Muscle power accounts for a greater amount of the variance in the level of mobility in older individuals than does muscle strength. Whole-body fat accounts for a greater amount of the variance in level of mobility than does whole-body lean tissue. Fat stored within muscle also appears to increase the risk of a mobility limitation in older individuals.
描述先前报道的与老年人活动能力相关的运动肌肉和全身组成因素。
对文献进行叙述性综述，包括与肌肉和全身组成因素以及老年人活动能力相关的搜索词组合。汇总关联和风险的统计测量结果，以总结各研究之间的共同效应。
共审查了53项研究。肌肉和全身因素在很大程度上解释了步行速度的变异性，决定系数范围为0.30至0.47。与力量相比，肌肉力量始终在活动能力差异中占更大比例。高脂肪量相关风险的最小比值比（OR）为0.70，最大OR为4.07，而低瘦体重相关的最小和最大OR分别为0.87和2.30。全身和局部脂肪沉积在很大程度上解释了活动能力的差异。
与肌肉力量相比，肌肉力量在老年人活动能力水平差异中占更大比例。与全身瘦组织相比，全身脂肪在活动能力水平差异中占更大比例。肌肉内储存的脂肪似乎也会增加老年人活动受限的风险。
