随机活检与靶向活检用于炎症性肠病的结直肠癌监测
Random versus targeted biopsies for colorectal cancer surveillance in inflammatory bowel disease.
作者信息
Ahmed Tasneem, Monti Jennifer, Lashner Bret
出版信息
Gastroenterol Hepatol (N Y). 2010 Jul;6(7):438-42.
Abstract
For many years, cancer surveillance colonoscopy in ulcerative colitis patients has involved obtaining at least 30 biopsies of flat and abnormal-appearing mucosa. With the advent of better imaging techniques, biopsies can be better targeted to abnormal-appearing mucosa, thereby increasing the sensitivity of testing. Use of chromoendoscopy, narrow-band imaging, autofluorescence, or confocal endomicroscopy to target biopsies is likely to improve detection of dysplasia and identification of patients at high risk for developing cancer.
摘要
多年来，溃疡性结肠炎患者的癌症监测结肠镜检查一直需要从平坦及外观异常的黏膜获取至少30块活检组织。随着更好的成像技术出现，活检可以更精准地针对外观异常的黏膜，从而提高检测的敏感性。使用染色内镜、窄带成像、自体荧光或共聚焦内镜显微镜来靶向活检，可能会改善发育异常的检测，并识别出患癌高风险患者。
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