UCLH Head and Neck Centre, London, UK.
Clin Oncol (R Coll Radiol). 2010 Nov;22(9):785-91. doi: 10.1016/j.clon.2010.07.001. Epub 2010 Sep 9.
End-stage head and neck cancer is a difficult disease to manage. The only curative treatment option remains surgery, but this is frequently not feasible. Often, however, significant palliation can be achieved with minimally invasive surgically directed treatments, such as photodynamic therapy. To avoid the morbidity of treating non-cancer areas, photodynamic therapy can now be very accurately directed by radiological imaging along pre-planned grids to document and optimise laser-guided photo-activation of the chemo-sensitiser. Rapid local tumour control often results, enabling the patient to benefit from both a higher quality and length of life.
晚期头颈部癌症是一种难以治疗的疾病。唯一的根治性治疗选择仍然是手术，但通常情况下，这种方法并不可行。然而，通过微创的手术治疗方法，如光动力疗法，可以实现显著的缓解。为了避免治疗非癌区域的发病率，可以通过预先规划的网格进行放射影像学指导，从而非常精确地引导光动力疗法，以记录和优化化疗增敏剂的激光引导光激活。这通常会导致肿瘤的快速局部控制，使患者能够从更高的生活质量和更长的寿命中受益。
