Clinical Sciences Division, ICDDR,B, Dhaka, Bangladesh.
Trop Med Int Health. 2010 Oct;15(10):1132-9. doi: 10.1111/j.1365-3156.2010.02608.x.
To determine the effectiveness of green banana in the home management of acute (<7 days) or prolonged (≥ 7 days) diarrhoea at the community level.
A cluster randomized field trial was conducted among 2968 Bangladeshi rural children 6-36 months old. Wards (villages) were randomly assigned to either a standard care group or a standard care plus green banana group where mothers were instructed to add cooked green banana to the diets of diarrhoeal children. Through a village-based surveillance system, diarrhoeal morbidity data (severity, duration, compliance) were collected for 14 days. Treatment effects were determined by analysing cumulative probability of cure by testing Cox proportional hazards models and relative risk (RR).
The cumulative probability of cure was significantly (P < 0.001) different in children receiving GB for both acute [hazard ratio (HR) = 0.63 (95% CI: 0.56-0.67)] and prolonged diarrhoea [HR = 0.38 (95% CI: 0.26-0.59)]. The recovery rates of children with acute diarrhoea receiving GB (vs. control) were significantly more by day 3: 79.9%vs. 53.3% [(RR) = 0.47, 95% CI: 0.41-0.55], (P < 0.001) and day 7: 96.6%vs. 89.1% (RR = 0.32; 0.22-0.46), (P < 0.001). Children with prolonged diarrhoea receiving green banana had significantly higher recovery rates by day 10: 79.8%vs. 51.9% (RR = 0.42; 0.23-0.73), (P < 0.001) and day 14: 93.6%vs. 67.2% (RR = 0.22; 0.08-0.54), (P < 0.001).
A green banana-supplemented diet hastened recovery of acute and prolonged childhood diarrhoea managed at home in rural Bangladesh.
摘要
确定在社区层面上，食用绿香蕉对急性（<7 天）或迁延性（≥7 天）腹泻的家庭管理的有效性。
对 2968 名 6-36 个月大的孟加拉国农村儿童进行了一项群组随机现场试验。将病房（村庄）随机分为标准护理组或标准护理加绿香蕉组，母亲们被指示在腹泻儿童的饮食中添加煮熟的绿香蕉。通过基于村庄的监测系统，在 14 天内收集腹泻发病率数据（严重程度、持续时间、依从性）。通过检验 Cox 比例风险模型和相对风险（RR）来确定治疗效果。
接受绿香蕉治疗的儿童，无论是急性腹泻（风险比（HR）=0.63（95%CI：0.56-0.67））还是迁延性腹泻（HR=0.38（95%CI：0.26-0.59）），其治愈的累积概率均有显著差异（P<0.001）。接受绿香蕉治疗的急性腹泻儿童，在第 3 天（RR=0.47，95%CI：0.41-0.55）和第 7 天（RR=0.32；0.22-0.46）的康复率明显更高（分别为 79.9%和 89.1%），（P<0.001）。接受绿香蕉治疗的迁延性腹泻儿童，在第 10 天（RR=0.42；0.23-0.73）和第 14 天（RR=0.22；0.08-0.54）的康复率明显更高（分别为 79.8%和 67.2%），（P<0.001）。
在孟加拉国农村，食用绿香蕉补充的饮食可加速急性和迁延性儿童腹泻的家庭管理的康复。
