Pharmacy Department, Grenoble University Hospital, France.
Crit Care Med. 2010 Dec;38(12):2275-81. doi: 10.1097/CCM.0b013e3181f8569b.
We aimed to assess the impact of an automated dispensing system on the incidence of medication errors related to picking, preparation, and administration of drugs in a medical intensive care unit. We also evaluated the clinical significance of such errors and user satisfaction.
Preintervention and postintervention study involving a control and an intervention medical intensive care unit.
Two medical intensive care units in the same department of a 2,000-bed university hospital.
Adult medical intensive care patients.
After a 2-month observation period, we implemented an automated dispensing system in one of the units (study unit) chosen randomly, with the other unit being the control.
The overall error rate was expressed as a percentage of total opportunities for error. The severity of errors was classified according to National Coordinating Council for Medication Error Reporting and Prevention categories by an expert committee. User satisfaction was assessed through self-administered questionnaires completed by nurses. A total of 1,476 medications for 115 patients were observed. After automated dispensing system implementation, we observed a reduced percentage of total opportunities for error in the study compared to the control unit (13.5% and 18.6%, respectively; p<.05); however, no significant difference was observed before automated dispensing system implementation (20.4% and 19.3%, respectively; not significant). Before-and-after comparisons in the study unit also showed a significantly reduced percentage of total opportunities for error (20.4% and 13.5%; p<.01). An analysis of detailed opportunities for error showed a significant impact of the automated dispensing system in reducing preparation errors (p<.05). Most errors caused no harm (National Coordinating Council for Medication Error Reporting and Prevention category C). The automated dispensing system did not reduce errors causing harm. Finally, the mean for working conditions improved from 1.0±0.8 to 2.5±0.8 on the four-point Likert scale.
The implementation of an automated dispensing system reduced overall medication errors related to picking, preparation, and administration of drugs in the intensive care unit. Furthermore, most nurses favored the new drug dispensation organization.
评估自动化配药系统对医疗重症监护病房药物分拣、准备和给药相关用药差错发生率的影响。我们还评估了这些差错的临床意义和用户满意度。
在设有对照的医疗重症监护病房进行的干预前和干预后研究。
同一家 2000 床位大学医院同一科室的两个医疗重症监护病房。
成年重症监护病房患者。
在为期 2 个月的观察期后,我们在其中一个单位(研究单位)随机实施了自动化配药系统,另一个单位为对照。
总差错率表示为总差错机会的百分比。差错的严重程度按照国家协调委员会药物差错报告和预防类别由专家委员会进行分类。通过护士自行填写的问卷评估用户满意度。共观察了 115 名患者的 1476 种药物。与对照单位相比,实施自动化配药系统后,研究单位的总差错机会百分比降低(分别为 13.5%和 18.6%;p<.05);然而,实施前差异无统计学意义(分别为 20.4%和 19.3%;无统计学意义)。研究单位的实施前后比较也显示总差错机会百分比显著降低(20.4%和 13.5%;p<.01)。详细差错机会分析显示,自动化配药系统在减少准备差错方面有显著影响(p<.05)。大多数差错未造成伤害(国家协调委员会药物差错报告和预防类别 C)。自动化配药系统并未减少造成伤害的差错。最后,工作条件的平均评分从 1.0±0.8 提高到 2.5±0.8(四点 Likert 量表)。
在重症监护病房实施自动化配药系统可减少与药物分拣、准备和给药相关的总体用药差错。此外,大多数护士赞成新的药物配发组织。