Department of Mechanical & Aerospace Engineering, University of Florida, Gainesville, Florida, USA.
J Orthop Res. 2010 Oct;28(10):1348-54. doi: 10.1002/jor.21142.
Excessive contact force is believed to contribute to the development of medial compartment knee osteoarthritis. The external knee adduction moment (KAM) has been identified as a surrogate measure for medial contact force during gait, with an abnormally large peak value being linked to increased pain and rate of disease progression. This study used in vivo gait data collected from a subject with a force-measuring knee implant to assess whether KAM decreases accurately predict corresponding decreases in medial contact force. Changes in both quantities generated via gait modification were analyzed statistically relative to the subject's normal gait. The two gait modifications were a "medial thrust" gait involving knee medialization during stance phase and a "walking pole" gait involving use of bilateral walking poles. Reductions in the first (largest) peak of the KAM (32-33%) did not correspond to reductions in the first peak of the medial contact force. In contrast, reductions in the second peak and angular impulse of the KAM (15-47%) corresponded to reductions in the second peak and impulse of the medial contact force (12-42%). Calculated reductions in both KAM peaks were highly sensitive to rotation of the shank reference frame about the superior-inferior axis of the shank. Both peaks of medial contact force were best predicted by a combination of peak values of the external KAM and peak absolute values of the external knee flexion moment (R(2) = 0.93). Future studies that evaluate the effectiveness of gait modifications for offloading the medial compartment of the knee should consider the combined effect of these two knee moments.
过度的接触力被认为是导致膝关节内侧间室骨关节炎发展的原因之一。膝关节外在内收力矩(KAM)已被确定为步态中内侧接触力的替代测量指标,其峰值异常增大与疼痛增加和疾病进展速度加快有关。本研究使用来自一位带有测力膝关节植入物的受试者的体内步态数据,评估 KAM 的减少是否能准确预测内侧接触力的相应减少。通过相对于受试者的正常步态对通过步态改变产生的两种变化进行统计学分析。两种步态改变是一种“内侧推进”步态,涉及在站立阶段使膝关节内侧化,以及一种“步行杆”步态,涉及使用双侧步行杆。KAM 的第一(最大)峰值的减少(32-33%)与内侧接触力的第一峰值的减少不对应。相比之下,KAM 的第二峰值和角动量的减少(15-47%)与内侧接触力的第二峰值和动量的减少(12-42%)对应。KAM 两个峰值的计算减少对小腿参考框架围绕小腿的上下轴的旋转高度敏感。内侧接触力的两个峰值都可以通过外部 KAM 的峰值和外部膝关节屈曲力矩的峰值绝对值(R(2) = 0.93)的组合来最佳预测。未来评估步态改变对内侧膝关节间室卸载效果的研究应考虑这两个膝关节力矩的综合影响。