Ferreira Wilton José, Amaro Rodrigo, Cavalcanti Diana Negrão, de Rezende Claudia Moraes, da Silva Viveca Antonia Giongo Galvão, Barbosa Juliana Eymara, Paixão Izabel Christina Nunes de Palmer, Teixeira Valéria Laneuville
Programa de Pós-Graduação em Química, Instituto de Química, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Nat Prod Commun. 2010 Aug;5(8):1167-70.
The CH2Cl2 crude extract and a fraction enriched with halogenated monoterpenes of the Brazilian red alga Plocamium brasiliense were evaluated for cytotoxicity and against the virus HSV-1. The extract showed low cytotoxicity compared with the fraction containing monoterpenes. The crude extract showed, in vitro, a high reduction of infectivity of the virus HSV-1.
对巴西红藻巴西团扇藻的二氯甲烷粗提物和富含卤代单萜的馏分进行了细胞毒性评估以及抗单纯疱疹病毒1型(HSV-1)的测试。与含有单萜的馏分相比,该提取物显示出较低的细胞毒性。粗提物在体外对HSV-1病毒的感染性有显著降低。