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Stem cells: Troublesome memories.

作者信息

Zwaka Thomas P

出版信息

Nature. 2010 Sep 16;467(7313):280-1. doi: 10.1038/467280a.

DOI:10.1038/467280a
PMID:20844526
Abstract
摘要

相似文献

1
Stem cells: Troublesome memories.干细胞:棘手的记忆。
Nature. 2010 Sep 16;467(7313):280-1. doi: 10.1038/467280a.
2
Epigenetic memory in induced pluripotent stem cells.诱导多能干细胞中的表观遗传记忆。
Nature. 2010 Sep 16;467(7313):285-90. doi: 10.1038/nature09342.
3
Flaw in induced-stem-cell model.诱导干细胞模型中的缺陷。
Nature. 2011 Feb 3;470(7332):13. doi: 10.1038/470013a.
4
The mysteries of induced pluripotency: where will they lead?诱导多能性的奥秘:它们将引领我们走向何方?
Nat Methods. 2010 Jan;7(1):22-4. doi: 10.1038/nmeth.f.292.
5
High throughput sequencing identifies an imprinted gene, Grb10, associated with the pluripotency state in nuclear transfer embryonic stem cells.高通量测序鉴定出一个与核移植胚胎干细胞多能性状态相关的印记基因Grb10。
Oncotarget. 2017 Jul 18;8(29):47344-47355. doi: 10.18632/oncotarget.17185.
6
Epigenetics of induced pluripotency, the seven-headed dragon.诱导多能干细胞的表观遗传学:七头龙。
Stem Cell Res Ther. 2010 Mar 15;1(1):3. doi: 10.1186/scrt3.
7
Stem cells: The dark side of induced pluripotency.干细胞:诱导多能性的阴暗面。
Nature. 2011 Mar 3;471(7336):46-7. doi: 10.1038/471046a.
8
Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity.人诱导多能干细胞系之间的表观遗传变异是分化能力的指标。
Cell Stem Cell. 2016 Sep 1;19(3):341-54. doi: 10.1016/j.stem.2016.06.019. Epub 2016 Jul 28.
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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells.人类诱导多能干细胞中异常表观基因组重编程的热点。
Nature. 2011 Mar 3;471(7336):68-73. doi: 10.1038/nature09798. Epub 2011 Feb 2.
10
Concise review: Induced pluripotent stem cells versus embryonic stem cells: close enough or yet too far apart?简明综述:诱导多能干细胞与胚胎干细胞:足够接近还是相差甚远?
Stem Cells. 2012 Jan;30(1):33-41. doi: 10.1002/stem.700.

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1
Epigenetic regulation and factors that influence the effect of iPSCs-derived neural stem/progenitor cells (NS/PCs) in the treatment of spinal cord injury.表观遗传调控及影响 iPS 细胞衍生的神经干细胞/祖细胞(NS/PCs)治疗脊髓损伤效果的因素。
Clin Epigenetics. 2024 Feb 21;16(1):30. doi: 10.1186/s13148-024-01639-5.
2
Strategic Application of Epigenetic Regulators for Efficient Neuronal Reprogramming of Human Fibroblasts.表观遗传调控因子在人类成纤维细胞高效神经元重编程中的策略性应用
Int J Stem Cells. 2023 May 30;16(2):156-167. doi: 10.15283/ijsc22183. Epub 2023 Feb 28.
3
Epigenetic memory in development and disease: Unraveling the mechanism.

本文引用的文献

1
Comprehensive methylome map of lineage commitment from haematopoietic progenitors.造血祖细胞向谱系定向分化的全甲基化组图谱
Nature. 2010 Sep 16;467(7313):338-42. doi: 10.1038/nature09367. Epub 2010 Aug 15.
2
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.通过定义因子将成纤维细胞直接重编程为功能性心肌细胞。
Cell. 2010 Aug 6;142(3):375-86. doi: 10.1016/j.cell.2010.07.002.
3
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells.细胞起源类型影响小鼠诱导多能干细胞的分子和功能特性。
发育与疾病中的表观遗传记忆:机制解析。
Biochim Biophys Acta Rev Cancer. 2020 Apr;1873(2):188349. doi: 10.1016/j.bbcan.2020.188349. Epub 2020 Jan 23.
4
Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast.首次细胞命运决定的表观遗传记忆可阻止胚胎干细胞完全重编程为滋养层细胞。
Nat Commun. 2014 Nov 26;5:5538. doi: 10.1038/ncomms6538.
5
Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines.多能基因的表观遗传调控介导人肝癌和癌细胞系中的干细胞特征。
PLoS One. 2013 Sep 4;8(9):e72435. doi: 10.1371/journal.pone.0072435. eCollection 2013.
6
Is belief larger than fact: expectations, optimism and reality for translational stem cell research.信念是否大于事实:转化干细胞研究的期望、乐观和现实。
BMC Med. 2012 Nov 6;10:133. doi: 10.1186/1741-7015-10-133.
7
Does transcription factor induced pluripotency accurately mimic embryo derived pluripotency?转录因子诱导的多能性是否准确模拟胚胎来源的多能性?
Curr Opin Genet Dev. 2012 Oct;22(5):429-34. doi: 10.1016/j.gde.2012.07.003. Epub 2012 Oct 15.
8
Impedance of novel therapeutic technologies: the case of stem cells.新型治疗技术的阻抗:以干细胞为例。
Clin Transl Sci. 2012 Oct;5(5):422-7. doi: 10.1111/j.1752-8062.2012.00434.x. Epub 2012 Jun 28.
9
Tinkering with transcription factors uncovers plasticity of somatic cells.对转录因子进行微调可揭示体细胞的可塑性。
Genes Cancer. 2010 Nov;1(11):1089-99. doi: 10.1177/1947601911401908.
10
The science and ethics of induced pluripotency: what will become of embryonic stem cells?诱导多能性的科学与伦理:胚胎干细胞将何去何从?
Mayo Clin Proc. 2011 Jul;86(7):634-40. doi: 10.4065/mcp.2011.0054.
Nat Biotechnol. 2010 Aug;28(8):848-55. doi: 10.1038/nbt.1667. Epub 2010 Jul 19.
4
Epigenetic memory in induced pluripotent stem cells.诱导多能干细胞中的表观遗传记忆。
Nature. 2010 Sep 16;467(7313):285-90. doi: 10.1038/nature09342.
5
LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?LINE-1 反转录转座子:神经元基因组体细胞变异的介体?
Trends Neurosci. 2010 Aug;33(8):345-54. doi: 10.1016/j.tins.2010.04.001. Epub 2010 May 12.
6
Direct conversion of fibroblasts to functional neurons by defined factors.通过定义因子将成纤维细胞直接转化为功能性神经元。
Nature. 2010 Feb 25;463(7284):1035-41. doi: 10.1038/nature08797. Epub 2010 Jan 27.
7
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.成年胰腺外分泌细胞在体内重编程为β细胞。
Nature. 2008 Oct 2;455(7213):627-32. doi: 10.1038/nature07314. Epub 2008 Aug 27.
8
Strategies and new developments in the generation of patient-specific pluripotent stem cells.生成患者特异性多能干细胞的策略与新进展。
Cell Stem Cell. 2007 Jun 7;1(1):39-49. doi: 10.1016/j.stem.2007.05.012.
9
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.通过特定因子从小鼠胚胎和成体成纤维细胞培养物中诱导多能干细胞。
Cell. 2006 Aug 25;126(4):663-76. doi: 10.1016/j.cell.2006.07.024. Epub 2006 Aug 10.
10
Nuclear reprogramming and pluripotency.细胞核重编程与多能性
Nature. 2006 Jun 29;441(7097):1061-7. doi: 10.1038/nature04955.