Department of General Surgery, Ninth People's Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai 200011, China.
Int J Biol Macromol. 2011 Jan 1;48(1):1-4. doi: 10.1016/j.ijbiomac.2010.09.004. Epub 2010 Sep 17.
Polysaccharides were extracted from Jisongrong mushroom. Jisongrong polysaccharides was a water-soluble compound. Its molecular weight was about 7.4×10(4) Da. HPLC analysis showed that this polysaccharides was composed of mannose, ribose, rhamnose, glucose, xylose, galactose and arabinose in the molar contents of 3.3, 17.3, 6.0, 12.4, 98.4 and 2.1 μM, respectively. In the range of 2800-3500 cm(-1), peaks at 2958 and 3407 cm(-1) belonging to -C-H of -CH2 groups, were observed in polysaccharides. When Jisongrong polysaccharides were orally administrated to rats for 2 months, level of lipid peroxidation products and activities of antioxidant enzymes in the blood were significantly decreased and enhanced compared to control rats. Moreover, Jisongrong polysaccharides still markedly inhibited cancer cells proliferation. These results suggested that Jisongrong polysaccharides possess a strong antioxidant and antitumour activities.
从鸡枞茸中提取了多糖。鸡枞茸多糖是一种水溶性化合物，其分子量约为 7.4×10(4) Da。HPLC 分析表明，这种多糖由摩尔含量分别为 3.3、17.3、6.0、12.4、98.4 和 2.1 μM 的甘露糖、核糖、鼠李糖、葡萄糖、木糖、半乳糖和阿拉伯糖组成。在 2800-3500 cm(-1)范围内，观察到多糖在 2958 和 3407 cm(-1)处存在属于-CH2 基团的-C-H 峰。当鸡枞茸多糖口服给予大鼠 2 个月时，与对照组大鼠相比，血液中脂质过氧化产物的水平和抗氧化酶的活性显著降低和增强。此外，鸡枞茸多糖仍能显著抑制癌细胞的增殖。这些结果表明，鸡枞茸多糖具有很强的抗氧化和抗肿瘤活性。
