CORE, Research Department of Clinical, Educational & Health Psychology, University College London, 19 Torrington Place, London WC1E 7HB, UK.
Fam Cancer. 2010 Dec;9(4):691-703. doi: 10.1007/s10689-010-9380-3.
This review of family communication of genetic risk information addresses questions of what the functions and influences on communication are; what, who and how family members are told about genetic risk information; what the impact for counsellee, relative and relationships are; whether there are differences by gender and condition; and what theories and methodologies are used. A systematic search strategy identified peer-reviewed journal articles published 1985-2009 using a mixture of methodologies. A Narrative Synthesis was used to extract and summarise data relevant to the research questions. This review identified 33 articles which found a consistent pattern of findings that communication about genetic risk within families is influenced by individual beliefs about the desirability of communicating genetic risk and by closeness of relationships within the family. None of the studies directly investigated the impact of communication on counsellees or their families, differences according to gender of counsellee or by condition nor alternative methods of communication with relatives. The findings mainly apply to late onset conditions such as Hereditary Breast and Ovarian Cancer. The most frequently used theory was Family Systems Theory and methods were generally qualitative. This review points to multifactorial influences on who is communicated with in families and what they are told about genetic risk information. Further research is required to investigate the impact of genetic risk information on family systems and differences between genders and conditions.
这篇关于遗传风险信息家庭沟通的综述探讨了沟通的功能和影响、向家庭成员传达遗传风险信息的内容、对象和方式、对咨询者、亲属和关系的影响、是否存在性别和疾病差异，以及使用了哪些理论和方法。采用混合方法的系统检索策略确定了 1985 年至 2009 年发表的同行评议期刊文章。采用叙述性综合方法提取和总结与研究问题相关的数据。这项综述确定了 33 篇文章，这些文章发现了一个一致的发现模式，即家庭内遗传风险沟通受到个体对沟通遗传风险的可取性的信念以及家庭内关系的密切程度的影响。没有一项研究直接调查沟通对咨询者或他们的家庭、咨询者的性别或疾病差异以及与亲属沟通的替代方法的影响。研究结果主要适用于遗传性乳腺癌和卵巢癌等迟发性疾病。最常使用的理论是家庭系统理论，方法通常是定性的。本综述指出了谁与家庭沟通以及向他们传达遗传风险信息的多因素影响。需要进一步研究来调查遗传风险信息对家庭系统的影响以及性别和疾病之间的差异。
