Martínez-Tovar José Gerardo, Rebollar-Téllez Eduardo A, Fernández Salas Ildefonso
Doctoral Student. Hospital General de Zona No 24, Instituto Mexicano del Seguro Social, Nueva RositaCoahuila, México, Doctoral Student. Hospital General de Zona No 24, Instituto Mexicano del Seguro Social, Nueva Rosita, Coahuila, México.
Laboratorio de Entomología Médica, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Medical Entomologist. Universidad Autónoma de Nuevo León. Facultad de Ciencias Biológicas. Laboratorio de Entomología Médica.
Rev Inst Med Trop Sao Paulo. 2014 Mar-Apr;56(2):169-74. doi: 10.1590/S0036-46652014000200014.
Chagas disease is considered a worldwide emerging disease; it is endemic in Mexico and the state of Coahuila and is considered of little relevance. The objective of this study was to determine the seroprevalence of T. cruzi infection in blood donors and Chagas cardiomyopathy in patients from the coal mining region of Coahuila, Mexico.
Epidemiological, exploratory and prospective study in a general hospital during the period January to June 2011.
We performed laboratory tests ELISA and indirect hemagglutination in three groups of individuals: 1) asymptomatic voluntary blood donors, 2) patients hospitalized in the cardiology department and 3) patients with dilated cardiomyopathy.
There were three levels of seroprevalence: 0.31% in asymptomatic individuals, 1.25% in cardiac patients and in patients with dilated cardiomyopathy in 21.14%.
In spite of having detected autochthonous cases of Chagas disease, its importance to local public health remains to be established as well as the details of the dynamics of transmission so that the study is still in progress.
恰加斯病被视为一种全球范围内的新兴疾病；在墨西哥和科阿韦拉州呈地方性流行，但被认为相关性不大。本研究的目的是确定墨西哥科阿韦拉州煤矿区献血者中克氏锥虫感染的血清流行率以及患者中恰加斯心肌病的情况。
2011年1月至6月期间在一家综合医院进行的流行病学、探索性和前瞻性研究。
我们对三组个体进行了酶联免疫吸附测定（ELISA）和间接血凝试验：1）无症状的自愿献血者，2）心内科住院患者，3）扩张型心肌病患者。
血清流行率有三个水平：无症状个体中为0.31%，心脏病患者中为1.25%，扩张型心肌病患者中为21.14%。
尽管已检测到恰加斯病的本土病例，但其对当地公共卫生的重要性以及传播动态细节仍有待确定，因此该研究仍在进行中。
