Research programme for Lifestyle and Health, National Institute of Public Health, University of Southern Denmark, Øster Farimagsgade 5A, 2nd floor, 1353 Copenhagen, Denmark.
Prev Med. 2010 Dec;51(6):471-5. doi: 10.1016/j.ypmed.2010.09.008. Epub 2010 Sep 19.
The objective of the study was to examine the role of leisure time physical activity on the risk of developing depression in a large longitudinal setting.
A prospective cohort study was used, comprising three updated measures of leisure time physical activity and covariates and 26 years of follow-up data on 18,146 individuals from the Copenhagen City Heart Study, Denmark. The study population was linked to two Danish hospital registers for information on depression. Data were collected in three rounds, namely, 1976-1978, 1981-1983, and 1991-1994, and analyses were conducted in 2010.
Compared to women with a high physical activity level, women with a moderate level had a hazard ratio of 1.07 (95% confidence interval: 0.80-1.44) for developing depression while women with a low level had a hazard ratio of 1.80 (95% confidence interval: 1.29-2.51). Compared to men with a high physical activity level, men with a moderate level had a hazard ratio of 1.11 (95% confidence interval: 0.73-1.68) for developing depression, while men with a low level had a hazard ratio of 1.39 (95% confidence interval: 0.83-2.34).
Among women, a low level of physical activity was significantly associated with a greater risk of depression.
本研究旨在探讨闲暇时间体力活动对丹麦哥本哈根城市心脏研究中 18146 名个体 26 年随访期间发生抑郁风险的影响。
采用前瞻性队列研究，包括三次更新的闲暇时间体力活动测量及协变量和 26 年随访数据。研究人群与丹麦两家医院的抑郁登记处相关联。数据在三个轮次收集，即 1976-1978 年、1981-1983 年和 1991-1994 年，分析于 2010 年进行。
与高体力活动水平的女性相比，中体力活动水平的女性发生抑郁的风险比为 1.07（95%置信区间：0.80-1.44），低体力活动水平的女性发生抑郁的风险比为 1.80（95%置信区间：1.29-2.51）。与高体力活动水平的男性相比，中体力活动水平的男性发生抑郁的风险比为 1.11（95%置信区间：0.73-1.68），低体力活动水平的男性发生抑郁的风险比为 1.39（95%置信区间：0.83-2.34）。
在女性中，低水平的体力活动与更大的抑郁风险显著相关。
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