Ermertcan Aylin Türel, Gencoglan Gulsum, Temeltas Gokhan, Horasan Gonul Dinc, Deveci Artuner, Ozturk Ferdi
Department of Dermatology, Celal Bayar University, Manisa, Turkey.
J Androl. 2011 Mar-Apr;32(2):165-9. doi: 10.2164/jandrol.110.010959. Epub 2010 Sep 23.
Neurodermatitis is a chronic disease affecting the patient's psychosocial status and quality of life. It is associated with a variety of psychologic problems, including demoralization, depression, anxiety, obsessive-compulsive disorder, and sleep disturbances. Coexistence of sexual dysfunction, especially in women, with several systemic diseases has gained interest in recent years. In this study, we evaluated sexual function in female patients with neurodermatitis. We enrolled 89 women (43 patients, 46 controls) in the study. Quality of life was assessed with the Dermatology Life Quality Index (DLQI), and the Female Sexual Function Index (FSFI) was used to determine sexual function. Individuals with psychiatric disorders and/or those using antidepressants were excluded. The total DLQI score was 11.95 ± 5.65 in patients with neurodermatitis. The total FSFI score was significantly lower in patients compared with healthy controls (22.76 ± 5.31 and 28.83 ± 3.50, respectively; P = .001). Domain scores of FSFI (desire, arousal, lubrication, orgasm, and satisfaction) except pain were significantly lower in patients with neurodermatitis (P = .001). The pain score was also lower in patients than controls, but the difference was not statistically significant (P = .073). Neurodermatitis may be associated with sexual dysfunction, and patients with neurodermatitis should be evaluated with regard to sexual function to provide a better quality of life.
神经性皮炎是一种影响患者心理社会状态和生活质量的慢性疾病。它与多种心理问题相关，包括士气低落、抑郁、焦虑、强迫症和睡眠障碍。近年来，性功能障碍尤其是女性性功能障碍与多种全身性疾病并存的情况受到了关注。在本研究中，我们评估了神经性皮炎女性患者的性功能。我们招募了89名女性（43例患者，46例对照）参与研究。使用皮肤病生活质量指数（DLQI）评估生活质量，并使用女性性功能指数（FSFI）来确定性功能。排除患有精神疾病和/或正在使用抗抑郁药的个体。神经性皮炎患者的DLQI总分为11.95±5.65。与健康对照相比，患者的FSFI总分显著更低（分别为22.76±5.31和28.83±3.50；P = 0.001）。除疼痛外，神经性皮炎患者FSFI的各领域得分（性欲、性唤起、润滑、性高潮和满意度）均显著更低（P = 0.001）。患者的疼痛得分也低于对照，但差异无统计学意义（P = 0.073）。神经性皮炎可能与性功能障碍有关，应对神经性皮炎患者的性功能进行评估，以提供更好的生活质量。
