University of Washington, School of Social Work, 4101 15th Avenue NE, Mailstop 354900, Seattle, WA 98105-6299, USA.
Prev Med. 2010 Dec;51(6):457-9. doi: 10.1016/j.ypmed.2010.09.010. Epub 2010 Sep 24.
To assess differences in weight regain one year after an 18-month obesity treatment with standard behavior therapy (SBT) or maintenance-tailored therapy for obesity (MTT).
213 obese adult volunteers were treated for 18 months using SBT with fixed behavioral prescriptions or MTT that employed varied behavioral prescriptions with treatment breaks. Follow-up analysis focused on weight maintenance after a year of no contact. The trial was conducted at the University of Minnesota between 2005 and 2009.
Mean (SD) weight change between 18 and 30 months for participants in the SBT group was +4.1 kg (4.4) compared to +2.8 kg (4.5) in the MTT group. This is a 31% reduction in weight regain in MTT relative to SBT (p=0.078). This trend toward better maintenance in MTT versus SBT was due primarily to superior differential maintenance in MTT participants in the highest tertile of total weight loss at 18 months, i.e. MTT participants in this tertile regained 4 kg less than SBT participants between 18 and 30 months.
The MTT approach with varied content and timing produced more desirable patterns of weight loss maintenance than the traditional SBT approach, especially among individuals who had achieved greater initial weight loss.
评估在标准行为疗法(SBT)或维持量身定制的肥胖治疗(MTT)治疗 18 个月后,一年后体重恢复的差异。
213 名肥胖成年志愿者接受 SBT 治疗 18 个月,SBT 采用固定行为处方,MTT 则采用不同的行为处方,并在治疗过程中休息。随访分析主要关注一年无接触后的体重维持情况。该试验于 2005 年至 2009 年在明尼苏达大学进行。
SBT 组参与者在 18 至 30 个月之间的平均(SD)体重变化为+4.1 公斤(4.4),而 MTT 组为+2.8 公斤(4.5)。这表明 MTT 组的体重恢复率比 SBT 组降低了 31%(p=0.078)。与 SBT 相比,MTT 在体重维持方面的这种趋势更好,主要是由于 MTT 组中 18 个月时总体重减轻最多的 tertile 参与者在维持方面表现更好,即在这个 tertile 中,MTT 参与者在 18 至 30 个月期间的体重恢复比 SBT 参与者少 4 公斤。
与传统的 SBT 方法相比,具有不同内容和时间的 MTT 方法产生了更理想的体重维持模式,特别是在初始体重减轻较多的个体中。