Department of Medicine, King Abdulaziz Hospital, National Guard Health Affairs, Saudi Arabia.
Saudi J Gastroenterol. 2010 Oct-Dec;16(4):264-7. doi: 10.4103/1319-3767.70610.
BACKGROUND/AIM: Earlier reports from Saudi Arabia have shown high prevalence of Helicobacter pylori infection. However, recent studies have documented a reduction in the infection prevalence. No prior study has assessed the prevalence in morbidly obese Saudi patients. We aimed to study the prevalence of H. pylori infection in a group morbidly obese Saudi patients referred for endoscopy prior to bariatric surgery.
We retrospectively reviewed the medical records of all patients who were referred for upper endoscopy prior to bariatric surgery from June 2006 to September 2008. All data were recorded including patient's demographics, comorbid conditions, endoscopic and histological findings.
There were 62 patients included, 20 males and 42 females. The mean age was 34 years (range 18-51) with a mean BMI of 55 Kg/m 2 (range 35-92). H. pylori were present in 53 patients (85.5%) with chronic active gastritis. All patients with positive H. pylori had chronic gastritis of variable severity. Intestinal metaplasia was present in 5%. The prevalence of H. pylori infection was similar in patients with and without co-morbid conditions. Main endoscopic findings were gastritis in 67.7%, hiatus hernia in 13%, and gastric erosions in 13%. No patient had duodenal or gastric ulcer.
There is a high prevalence of H. pylori infection in morbidly obese Saudi patients undergoing bariatric surgery being referred for upper GI endoscopy. Further prospective studies are needed to evaluate the clinical implication and benefit of eradication treatment of infection in these patients.
背景/目的：沙特阿拉伯的早期报告显示，幽门螺杆菌感染的流行率很高。然而，最近的研究已经记录到感染流行率的降低。以前没有研究评估过病态肥胖的沙特患者的感染流行率。我们旨在研究一组病态肥胖的沙特患者在接受减肥手术前接受内镜检查时感染 H. pylori 的流行率。
我们回顾性审查了 2006 年 6 月至 2008 年 9 月期间因减肥手术前接受上消化道内镜检查的所有患者的病历。记录了所有数据，包括患者的人口统计学特征、合并症、内镜和组织学发现。
共纳入 62 例患者，男 20 例，女 42 例。平均年龄为 34 岁（范围 18-51 岁），平均 BMI 为 55 Kg/m 2（范围 35-92）。53 例（85.5%）患者存在 H. pylori，伴有慢性活动性胃炎。所有 H. pylori 阳性患者均有不同程度的慢性胃炎。肠化生发生率为 5%。有合并症的患者与无合并症的患者的 H. pylori 感染率相似。主要内镜发现为胃炎 67.7%、食管裂孔疝 13%、胃糜烂 13%。无患者患有十二指肠或胃溃疡。
在接受减肥手术前接受上消化道内镜检查的病态肥胖的沙特患者中，H. pylori 感染的流行率很高。需要进一步的前瞻性研究来评估这些患者感染根除治疗的临床意义和益处。
