Department of Health Policy and Management, University of Pittsburgh, 130 De Soto Street, Crabtree Hall A664, Pittsburgh, PA 15261, USA.
Health Serv Res. 2011 Feb;46(1 Pt 1):185-98. doi: 10.1111/j.1475-6773.2010.01183.x. Epub 2010 Sep 28.
To evaluate Medicare Part D's impact on use of antihypertensive medications among seniors with hypertension.
Medicare-Advantage plan pharmacy data from January 1, 2004 to December 12, 2007 from three groups who before enrolling in Part D had no or limited drug benefits, and a comparison group with stable employer-based coverage.
Pre-post intervention with a comparison group design was used to study likelihood of use, daily counts, and substitutions between angiotensin-converting enzyme inhibitors and angiotensin-II receptor blockers (ARBs).
Antihypertensive use increased most among those without prior drug coverage: likelihood of use increased (odds ratio = 1.40, 95 percent confidence interval [CI] 1.25-1.56), and daily counts increased 0.29 (95 percent CI 0.24-0.33). Proportion using ARBs increased from 40 to 46 percent.
Part D was associated with increased antihypertensive use and use of ARBs over less expensive alternatives.
评估医疗保险处方药部分(Medicare Part D)对高血压老年患者使用抗高血压药物的影响。
2004 年 1 月 1 日至 2007 年 12 月 12 日,来自三组老年人的医疗保险优势计划药房数据,这三组老年人在参加处方药部分之前没有或只有有限的药物福利,以及一组具有稳定雇主为基础的覆盖范围的比较组。
使用前后干预与比较组设计来研究使用的可能性、每日用量和血管紧张素转换酶抑制剂和血管紧张素 II 受体阻滞剂(ARBs)之间的替代情况。
在没有先前药物覆盖的人群中,抗高血压药物的使用增加最多:使用的可能性增加(优势比=1.40,95%置信区间[CI]为 1.25-1.56),每日用量增加 0.29(95%CI 为 0.24-0.33)。使用 ARBs 的比例从 40%增加到 46%。
处方药部分与增加抗高血压药物的使用和使用更便宜的替代药物的 ARBs 有关。