Department of Otolaryngology, Sahlgrenska University Hospital, Goteborg University, Goteborg, Sweden.
Med Sci Monit. 2010 Oct;16(10):CR480-7.
The aim of this study was to adapt the Laryngopharyngeal Reflux Health- Related Quality of Life questionnaire (LPR-HRQL) to Swedish and evaluate its psychometric properties in patients with suspected laryngopharyngeal reflux (LPR).
MATERIAL/METHODS: The psychometric validation included 228 patients with suspected LPR who had previously undergone a 2-level 24-hour pH examination and who answered a mail-distributed set of questionnaires. The patients were divided into 2 comparable groups according to the Reflux Symptom Index (RSI) cut-off score: 126 patients with RSI score between 0-13 (defined as normal) and 102 patients with RSI score >13 (defined as abnormal, i.e. having LPR disease).
LPR-HRQL was adapted to Swedish using a formal forward-backward translation method with input from expert groups (patients and physicians). Psychometric properties of the Swedish version of LPR-HRQL were evaluated by using factor analysis to explore the factor structure. Convergent and discriminant validity was determined by using the questionnaires RSI and Short Form-36 (SF-36). The psychometric tests performed fulfilled the criteria for structural integrity, validity and reliability, mostly confirming the results obtained in the original LPR-HRQL version.
The Swedish translated version of LPR-HRQL proved to be a statistically valid instrument with which to assess HRQL in patients with LPR disease, and will be further tested in prospective studies.
本研究旨在将喉咽反流健康相关生活质量问卷（LPR-HRQL）翻译成瑞典语，并评估其在疑似喉咽反流（LPR）患者中的心理测量特性。
材料/方法：心理测量验证包括 228 名疑似 LPR 患者，这些患者之前曾接受过 2 级 24 小时 pH 检查，并通过邮件分发了一组问卷。根据反流症状指数（RSI）的临界值评分，将患者分为 2 个可比组：RSI 评分在 0-13 之间的 126 名患者（定义为正常）和 RSI 评分>13 的 102 名患者（定义为异常，即患有 LPR 疾病）。
LPR-HRQL 通过使用正向-反向翻译方法进行了瑞典语的改编，专家组（患者和医生）提供了输入。使用因子分析来探索因子结构，评估了瑞典语版 LPR-HRQL 的心理测量特性。使用问卷 RSI 和简明健康调查问卷（SF-36）确定了收敛和判别有效性。进行的心理测量测试满足结构完整性、有效性和可靠性的标准，大部分结果与原始 LPR-HRQL 版本的结果一致。
LPR-HRQL 的瑞典语翻译版本被证明是一种统计学上有效的工具，可用于评估 LPR 疾病患者的 HRQL，并将在未来的研究中进一步测试。
