Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, USA.
Chem Soc Rev. 2010 Dec;39(12):4560-70. doi: 10.1039/b909052p. Epub 2010 Oct 1.
This tutorial review covers recent developments in using single-molecule fluorescence microscopy to study nanoscale catalysis. The single-molecule approach enables following catalytic and electrocatalytic reactions on nanocatalysts, including metal nanoparticles and carbon nanotubes, at single-reaction temporal resolution and nanometer spatial precision. Real-time, in situ, multiplexed measurements are readily achievable under ambient solution conditions. These studies provide unprecedented insights into catalytic mechanism, reactivity, selectivity, and dynamics in spite of the inhomogeneity and temporal variations of catalyst structures. Prospects, generality, and limitations of the single-molecule fluorescence approach for studying nanocatalysis are also discussed.
本教程综述涵盖了使用单分子荧光显微镜研究纳米尺度催化反应的最新进展。单分子方法能够以单反应时间分辨率和纳米空间精度跟踪纳米催化剂（包括金属纳米粒子和碳纳米管）上的催化和电催化反应。在环境溶液条件下，可以很容易地实现实时、原位、多重测量。这些研究尽管催化剂结构存在不均匀性和时间变化，但还是提供了对催化机制、反应性、选择性和动力学的前所未有的见解。还讨论了用于研究纳米催化的单分子荧光方法的前景、通用性和局限性。
