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格氏巴利综合征病毒:沙蝇热那不勒斯血清群的一种天然白蛉病毒重组体,人群中血清流行率较低。

Granada virus: a natural phlebovirus reassortant of the sandfly fever Naples serocomplex with low seroprevalence in humans.

机构信息

Department of Virology, National Center of Microbiology, Institute of Health Carlos III, Madrid, Spain.

出版信息

Am J Trop Med Hyg. 2010 Oct;83(4):760-5. doi: 10.4269/ajtmh.2010.09-0697.

Abstract

A new member of the phlebovirus genus, tentatively named Granada virus, was detected in sandflies collected in Spain. By showing the presence of specific neutralizing antibodies in human serum collected in Granada, we show that Granada virus infects humans. The analysis of the complete genome of Granada virus revealed that this agent is likely to be a natural reassortant of the recently described Massilia virus (donor of the long and short segments) with a yet unidentified phlebovirus (donor of the medium segment).

摘要

在西班牙采集的沙蝇中发现了一种新的属,暂定名为 Granada 病毒。通过显示在格拉纳达采集的人血清中存在特定的中和抗体,我们表明 Granada 病毒感染人类。对 Granada 病毒完整基因组的分析表明,该病原体可能是最近描述的马西利亚病毒(长和短片段的供体)与尚未鉴定的节肢动物病毒(中片段的供体)的天然重组体。

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