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老年男性雄激素缺乏

Androgen deficiency in the aging man.

作者信息

Arianayagam Ranjan, Arianayagam Mohan, McGrath Shaun, Rashid Prem

机构信息

Royal North Shore Hospital, Sydney, New South Wales.

出版信息

Aust Fam Physician. 2010 Oct;39(10):752-5.

PMID:20890477
Abstract

BACKGROUND

Androgen deficiency in the aging man is an area of considerable debate because a gradual decline in testosterone may simply be part of the normal aging process. However, there is an alternative view that androgen deficiency in the aging man may constitute a valid and underdiagnosed disorder.

OBJECTIVE

To discuss the aetiology, clinical features, diagnosis and management of androgen deficiency in the aging man.

DISCUSSION

Late onset hypogonadism has clinical features that overlap with both normal aging and some pathological conditions. It can only be diagnosed on the basis of both suggestive clinical features and clear biochemical evidence of testosterone deficiency. In this group of patients medication may play a role.

摘要

背景

老年男性雄激素缺乏是一个备受争议的领域,因为睾酮水平的逐渐下降可能仅仅是正常衰老过程的一部分。然而,另一种观点认为,老年男性雄激素缺乏可能是一种真实存在但未被充分诊断的疾病。

目的

探讨老年男性雄激素缺乏的病因、临床特征、诊断及治疗。

讨论

迟发性性腺功能减退的临床特征与正常衰老及某些病理状况存在重叠。只有在具备提示性临床特征及明确的睾酮缺乏生化证据的基础上才能做出诊断。在这类患者中,药物可能会发挥作用。

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