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关节炎成人的睡眠障碍:患病率、中介因素和高危亚组。来自 2007 年全国健康访谈调查的数据。

Sleep disturbances in adults with arthritis: prevalence, mediators, and subgroups at greatest risk. Data from the 2007 National Health Interview Survey.

机构信息

National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

出版信息

Arthritis Care Res (Hoboken). 2011 Feb;63(2):247-60. doi: 10.1002/acr.20362.

Abstract

OBJECTIVE

To examine the prevalence of sleep disturbances in adults with arthritis in a nationally representative sample, mediators of sleep difficulties, and subgroups of individuals with arthritis at greatest risk.

METHODS

Using data on US adults ages≥18 years participating in the 2007 National Health Interview Survey, we computed the prevalence of 3 measures of sleep disturbance (insomnia, excessive daytime sleepiness, and sleep duration<6 hours) among persons with arthritis. We used logistic regression analysis to examine if the association of arthritis and sleep disturbances was independent of sociodemographic characteristics and comorbidities, and to identify potential mediators. We used classification trees to identify subgroups at higher risk.

RESULTS

The adjusted prevalence of insomnia was higher among adults with arthritis than those without arthritis (23.1% versus 16.4%; P<0.0001), but was similar to those with other chronic diseases. Adults with arthritis were more likely than those without arthritis to report insomnia (unadjusted odds ratio 2.92, 95% confidence interval 2.68-3.17), but adjustment for sociodemographic characteristics and comorbidities attenuated this association. Joint pain and limitation due to pain mediated the association between arthritis and insomnia. Among adults with arthritis, those with depression and anxiety were at highest risk for sleep disturbance. Results for excessive daytime sleepiness and sleep duration<6 hours were similar.

CONCLUSION

Sleep disturbance affects up to 10.2 million US adults with arthritis, and is mediated by joint pain and limitation due to pain. Among individuals with arthritis, those with depression and anxiety are at greatest risk.

摘要

目的

在全国代表性样本中调查关节炎成年人睡眠障碍的流行情况、睡眠困难的中介因素以及关节炎风险最高的亚组人群。

方法

使用参与 2007 年全国健康访谈调查的美国≥18 岁成年人的数据,我们计算了关节炎患者中 3 种睡眠障碍(失眠、日间嗜睡过多和睡眠时长<6 小时)的流行率。我们使用逻辑回归分析来检查关节炎与睡眠障碍之间的关联是否独立于社会人口统计学特征和合并症,并确定潜在的中介因素。我们使用分类树来确定风险较高的亚组人群。

结果

关节炎成年人的失眠调整后流行率高于无关节炎成年人(23.1%对 16.4%;P<0.0001),但与其他慢性疾病相似。与无关节炎成年人相比,关节炎成年人更有可能报告失眠(未经调整的优势比 2.92,95%置信区间 2.68-3.17),但调整社会人口统计学特征和合并症后,这种关联减弱。关节疼痛和疼痛导致的活动受限中介了关节炎与失眠之间的关联。在关节炎成年人中,患有抑郁和焦虑的人睡眠障碍风险最高。日间嗜睡过多和睡眠时长<6 小时的结果相似。

结论

睡眠障碍影响了多达 1020 万美国关节炎成年人,由关节疼痛和疼痛导致的活动受限介导。在关节炎患者中,患有抑郁和焦虑的人风险最高。

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