一种大肠杆菌细胞毒素的特性。
Properties of an Escherichia coli cytotoxin.
作者信息
Konowalchuk J, Dickie N, Stavric S, Speirs J I
出版信息
Infect Immun. 1978 May;20(2):575-7. doi: 10.1128/iai.20.2.575-577.1978.
Abstract
Isoelectric focusing of a heat-labile cytotoxin of Escherichia coli H30 revealed the presence of two molecular variants, pI 7.2 and a comparatively small quantity of pI 6.8. Predominant component pI 7.2 had a molecular weight of 28,000, induced some fluid accumulation in rabbit ileal loops, and showed no morphological response in Y-1 cells but a strong cytotoxic effect on Vero cells.
摘要
对大肠杆菌H30的一种热不稳定细胞毒素进行等电聚焦分析，结果显示存在两种分子变体，等电点分别为7.2和6.8（含量相对较少）。主要成分等电点7.2，分子量为28,000，可引起兔回肠袢出现一些液体蓄积，对Y-1细胞无形态学反应，但对Vero细胞有强烈的细胞毒性作用。
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