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失代偿期肝硬化合并“紧张性”腹水患者的自发性细菌性腹膜炎

[Spontaneous bacterial peritonitis in patients with decompensated liver cirrhosis and "tense" ascites].

作者信息

Rotkvić I, Sikirić P, Jukić J, Krizanac S, Zjacić-Rotkvić V, Anić T, Duvnjak M, Mise S, Knezević S

机构信息

Radne jedinice "Interna" Opće bolnice, Dr. Josip Kajfes, Zagrebu.

出版信息

Acta Med Iugosl. 1990;44(4):285-95.

PMID:2091434
Abstract

In the study 52 patients with decompensated liver cirrhosis and "tense" ascites were included. According to the clinical picture, ascites cultures and the number of polymorphonuclears in cmm of the ascitic fluid, all patients were selected in one of the following groups: 1. group of patients with sterile ascites (28), 2. group of patients with spontaneous peritonitis (16), and 3. group of patients with bacterascites (8). The results have shown that the incidence of spontaneous peritonitis is much higher in the group of "tense" ascites patients than in the group of all patients with ascites, the ratio being 30.7% compared to 6% in all cirrhotic patients with ascites. Spontaneous bacterial peritonitis correlates with increased polymorphonuclears in the ascitic fluid (p less than 0.05), decreased pH values (p less than 0.0), and increased amounts of total proteins in the ascitic fluid (p less than 0.05). The lethality rate in the group of spontaneous peritonitis and sterile ascites was 43.7% and 7.1% respectively. Early diagnosis and, of course, adequate therapy are the main points in spontaneous bacterial peritonitis.

摘要

该研究纳入了52例失代偿期肝硬化且伴有“紧张性”腹水的患者。根据临床表现、腹水培养结果以及每立方毫米腹水中多形核白细胞的数量,所有患者被分为以下几组之一:1. 无菌性腹水患者组(28例),2. 自发性腹膜炎患者组(16例),3. 细菌性腹水患者组(8例)。结果显示,“紧张性”腹水患者组中自发性腹膜炎的发生率远高于所有腹水患者组,比例分别为30.7%和6%(所有肝硬化腹水患者)。自发性细菌性腹膜炎与腹水中多形核白细胞增多(p<0.05)、pH值降低(p<0.0)以及腹水中总蛋白量增加(p<0.05)相关。自发性腹膜炎组和无菌性腹水组的致死率分别为43.7%和

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Acta Med Iugosl. 1990;44(4):285-95.
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