Suppr超能文献

儿茶酚胺心肌病:发病机制的综述与分析

Catecholamine cardiomyopathy: review and analysis of pathogenetic mechanisms.

作者信息

Jiang J P, Downing S E

机构信息

Department of Pathology, Yale University School of Medicine, New Haven, CT 06510.

出版信息

Yale J Biol Med. 1990 Nov-Dec;63(6):581-91.

Abstract

Catecholamines given in high concentrations produce myocardial damage in several mammalian species. The histological changes are similar to those found in patients given large amounts of pressor agents and in those who develop pheochromocytomas. They include myofiber necrosis, myofibrillar degeneration, and mononuclear leukocytic infiltration. Cardiac function is significantly impaired. Endogenous release of catecholamines can also induce myocardial injury in rabbits infused with tyramine. Anatomic and functional abnormalities described in various models of catecholamine cardiomyopathy are summarized. The several major theories regarding pathogenesis are reviewed. Recent data suggesting that O2-derived free radical generation is involved are discussed.

摘要

高浓度给予的儿茶酚胺会在几种哺乳动物物种中造成心肌损伤。组织学变化类似于接受大量升压药的患者以及患有嗜铬细胞瘤的患者中发现的变化。这些变化包括肌纤维坏死、肌原纤维变性和单核白细胞浸润。心脏功能会受到显著损害。内源性儿茶酚胺的释放也可在输注酪胺的兔子中诱发心肌损伤。总结了儿茶酚胺心肌病各种模型中描述的解剖学和功能异常。回顾了关于发病机制的几种主要理论。讨论了近期表明涉及氧衍生自由基生成的数据。

相似文献

3
Catecholamine cardiotoxicity.儿茶酚胺心脏毒性
J Mol Cell Cardiol. 1985 Apr;17(4):291-306. doi: 10.1016/s0022-2828(85)80130-9.
4
Myocardial diseases of animals.动物的心肌疾病
Am J Pathol. 1986 Jul;124(1):98-178.
6
Membrane damage and the pathogenesis of cardiomyopathies.膜损伤与心肌病的发病机制
J Mol Cell Cardiol. 1985 Jul;17 Suppl 2:11-20. doi: 10.1016/0022-2828(85)90004-5.
7
Essential contribution of thrombocytes to the occurrence of catecholamine-induced cardiac necroses.
J Mol Cell Cardiol. 1985 Apr;17(4):371-6. doi: 10.1016/s0022-2828(85)80136-x.

引用本文的文献

3
Cardiovascular disease associated with methamphetamine use: a review.与使用甲基苯丙胺相关的心血管疾病:综述
Heart Fail Rev. 2022 Nov;27(6):2059-2065. doi: 10.1007/s10741-022-10261-7. Epub 2022 Jul 18.
8
Takotsubo-Like Cardiomyopathy in Pheochromocytoma.嗜铬细胞瘤中的应激性心肌病样心肌病
CASE (Phila). 2019 May 23;3(4):157-161. doi: 10.1016/j.case.2019.04.006. eCollection 2019 Aug.

本文引用的文献

3
VARIABILITY IN THE AGGREGATION OF HUMAN PLATELETS OY ADRENALINE.
Nature. 1964 Jun 20;202:1188-90. doi: 10.1038/2021188a0.
6
PLATELET CLUMPING IN VITRO.体外血小板聚集
Br J Haematol. 1964 Jan;10:78-93. doi: 10.1111/j.1365-2141.1964.tb00681.x.
9
Pathologic changes induced by 1-norepineprine: quantitative aspects.
Am J Cardiol. 1960 May;5:619-27. doi: 10.1016/0002-9149(60)90127-2.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验