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改良 Chrispin-Norman 胸部 X 射线评分系统在囊性纤维化中的应用:观察者间一致性及与肺功能的相关性。

Modified Chrispin-Norman chest radiography score for cystic fibrosis: observer agreement and correlation with lung function.

机构信息

Department of Radiology, University Medical Center Utrecht and Wilhelmina Children's Hospital, HP E.01.132, Heidelberglaan 100, 3584 CX Utrecht, Netherlands.

出版信息

Eur Radiol. 2011 Apr;21(4):722-9. doi: 10.1007/s00330-010-1972-7. Epub 2010 Oct 6.

Abstract

OBJECTIVE

To test observer agreement and two strategies for possible improvement (consensus meeting and reference images) for the modified Chrispin-Norman score for children with cystic fibrosis (CF).

METHODS

Before and after a consensus meeting and after developing reference images three observers scored sets of 25 chest radiographs from children with CF. Observer agreement was tested for line, ring, mottled and large soft shadows, for overinflation and for the composite modified Chrispin-Norman score. Correlation with lung function was assessed.

RESULTS

Before the consensus meeting agreement between observers 1 and 2 was moderate-good, but with observer 3 agreement was poor-fair. Scores correlated significantly with spirometry for observers 1 and 2 (-0.72<R<-0.42, P < 0.05), but not for observer 3. Agreement with observer 3 improved after the consensus meeting. Reference images improved agreement for overinflation and mottled and large shadows and correlation with lung function, but agreement for the modified Chrispin-Norman score did not improve further.

CONCLUSION

Consensus meetings and reference images improve among-observer agreement for the modified Chrispin-Norman score, but good agreement was not achieved among all observers for the modified Chrispin-Norman score and for bronchial line and ring shadows.

摘要

目的

测试改良的 Chrispin-Norman 评分在囊性纤维化(CF)儿童中的观察者间一致性和两种可能的改进策略(共识会议和参考图像)。

方法

在共识会议之前、之后以及参考图像开发之后,三位观察者对 25 组 CF 儿童的胸部 X 光片进行评分。测试了线影、环影、斑驳影和大阴影、过度充气以及改良的 Chrispin-Norman 综合评分的一致性。评估了与肺功能的相关性。

结果

在共识会议之前,观察者 1 和 2 之间的一致性为中-好,但与观察者 3 的一致性为差-一般。评分与观察者 1 和 2 的肺功能测定显著相关(-0.72<R<-0.42,P<0.05),但与观察者 3 无关。共识会议后,与观察者 3 的一致性得到改善。参考图像改善了过度充气和斑驳影和大阴影以及与肺功能的相关性的一致性,但改良的 Chrispin-Norman 评分的一致性没有进一步提高。

结论

共识会议和参考图像提高了改良的 Chrispin-Norman 评分的观察者间一致性,但对于改良的 Chrispin-Norman 评分以及支气管线影和环影,并非所有观察者都能达到良好的一致性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d139/3047050/e3496bb8c43d/330_2010_1972_Fig1_HTML.jpg

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