Suppr超能文献

[有功能障碍和无功能障碍的二尖瓣人工瓣膜:二维多普勒超声心动图评估]

[Mitral prostheses with and without dysfunction: evaluation using 2-D Doppler echocardiography].

作者信息

Bernardes L, Abreu J, Soares R, Matos P, Ramos J S, Salomão S

机构信息

Serviço de Cardiologia, Hospital de Santa Marta, Lisboa.

出版信息

Rev Port Cardiol. 1990 Dec;9(12):973-9.

PMID:2093337
Abstract

STUDY OBJECTIVE

To evaluate the flow characteristics of normal and abnormal functioning mechanical and bioprosthetic (B) mitral valves.

DESIGN

Prospective study in patients submitted to mitral valve replacement.

SETTING

Laboratory of Echocardiography at Santa Marta Hospital.

PATIENTS

61 consecutive and asymptomatic patients with normally functioning mitral prosthesis (prt)--37 Bjork-Shiley (B-S), 11 Carpentier-Edwards (C-E), 5 Hancok (HAN), 7 Ionescu-Shiley (I-S) and 1 Wessex--and 15 pts with abnormal prosthetic function (6 B-S, 5 Hall-Kaster, 2 C-E, 1 I-S and 1 HAN).

INTERVENTION

Prosthetic mitral flow record, using 2D-Doppler echocardiography, to analyse: peak velocity (PV), peak gradient (PG), mean gradient (MG), pressure half time (PHT), area (A) and presence of regurgitation (R).

RESULTS

Normally functioning prosthetic valves--PV ranged from 88 to 186 cm/s (134.6 +/- 24.3) in B-S prt and 133 to 198 cm/s (157.4 +/- 18.8) in B, p less than 0.0001. The prt B-S showed a greater PG (10.3 +/- 2.5 vs 7.6 +/- 2.6 mmHg), MG (3.1 +/- 1.1 vs 2.6 +/- 1 mmHg) and smaller area (2.3 +/- 0.4 vs 2.5 +/- 0.4 cm2) then Bioprosthetic ones, p less than 0.0001, p = 0.003, p = 0.003 respectively. There was a significant correlation between PG and MG: r = 0.84, r = 0.87, r = 0.84 respectively in B-S prt, Bioprosthesis and both, p less than 0.001. Mild regurgitation was present in 8 pts with prt B-S and 4 with B. Malfunctioning prosthetic valves--The mean of PV was 238.5 +/- 29.2 cm/s in prt B-S compared to 265.48.2 +/- 48.2 cm/s in B. Significant regurgitation, was detected by Doppler technic in 100% of B and 72% of mechanical prt. PV greater than 2 m/s has a 100% sensitivity and specificity to separate normal from abnormal prosthesis function.

CONCLUSIONS

These data may be useful as reference values to the follow-up of pts with these types of prt. The prt B-S seems to have more optimal hemodynamics profile than B ones. Protodiastolic transprosthetic PV greater than 2 m/s suggest abnormal functioning valve. PG is a significant determinant of MG.

摘要

研究目的

评估正常及异常功能的机械二尖瓣和生物瓣的血流特性。

设计

对接受二尖瓣置换术的患者进行前瞻性研究。

地点

圣玛尔塔医院超声心动图实验室。

患者

61例连续且无症状的二尖瓣人工瓣膜功能正常的患者(假体)——37例 Bjork-Shiley(B-S)型、11例Carpentier-Edwards(C-E)型、5例Hancok(HAN)型、7例Ionescu-Shiley(I-S)型和1例Wessex型,以及15例人工瓣膜功能异常的患者(6例B-S型、5例Hall-Kaster型、2例C-E型、1例I-S型和1例HAN型)。

干预措施

采用二维多普勒超声心动图记录人工二尖瓣血流,以分析:峰值速度(PV)、峰值压差(PG)、平均压差(MG)、压力减半时间(PHT)、面积(A)及反流情况(R)。

结果

人工瓣膜功能正常者——B-S型假体的PV范围为88至186cm/s(134.6±24.3),生物瓣为133至198cm/s(157.4±18.8),p<0.0001。B-S型假体的PG(10.3±2.5对7.6±2.6mmHg)、MG(3.1±1.1对2.6±1mmHg)更高,面积(2.3±0.4对2.5±0.4cm²)更小,与生物瓣相比,p分别为<0.0001、p = 0.003、p = 0.003。PG与MG之间存在显著相关性:B-S型假体、生物瓣及两者总体的r分别为0.84、0.87、0.84,p<0.001。8例B-S型假体和4例生物瓣患者存在轻度反流。人工瓣膜功能异常者——B-S型假体的PV平均值为238.5±29.2cm/s,生物瓣为265.4±48.2cm/s。通过多普勒技术检测,100%的生物瓣和72%的机械假体存在显著反流。PV大于2m/s对区分正常与异常假体功能具有100%的敏感性和特异性。

结论

这些数据可作为这类假体患者随访的参考值。B-S型假体似乎比生物瓣具有更优的血流动力学特征。舒张前期经人工瓣膜PV大于2m/s提示瓣膜功能异常。PG是MG的重要决定因素。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验