Department of Surgery, Hallym University College of Medicine, Anyang 431-070, South Korea.
World J Gastroenterol. 2010 Oct 14;16(38):4854-7. doi: 10.3748/wjg.v16.i38.4854.
To compare the recurrence rate following initial antibiotic management to that following laparoscopic treatment for suspected uncomplicated cecal diverticulitis.
We examined the records of 132 patients who were diagnosed with uncomplicated cecal diverticulitis and a first attack during an 8-year period. The diagnosis of uncomplicated diverticulitis was made based on imaging findings, such as inflamed diverticulum or a phlegmon with cecal wall thickening. Concurrent appendiceal dilatation from 8 to 12 mm was observed in 36 patients (27%). One hundred and two patients were treated initially with antibiotics only, whereas 30 underwent laparoscopic treatment, including partial cecectomy (n = 8) or appendectomy with diverticulectomy (n = 9) or appendectomy alone (n = 13). We compared clinical outcomes in both groups over a median follow-up period of 46 mo.
All patients were successfully treated with initial therapy. Of the 102 patients who initially received only antibiotic treatment, 6 (6%) had a recurrence (3 in the cecum and 3 in the ascending colon or transverse colon) during the follow-up period. Five of these patients were managed with repeated antibiotic treatment and 1 underwent ileocolic resection for perforation. Of the 30 patients treated by the laparoscopic approach, 2 (7%) had a recurrence (ascending colon) which was treated with antibiotics.
Initial antibiotic management for suspected uncomplicated cecal diverticulitis showed comparable efficacy to laparoscopic treatment in the prevention of recurrence.
比较初始抗生素治疗后与疑似单纯性盲肠憩室炎的腹腔镜治疗后复发率。
我们检查了 132 例患者的记录,这些患者在 8 年期间被诊断为单纯性盲肠憩室炎和首次发作。单纯性憩室炎的诊断基于影像学发现,例如发炎的憩室或伴有盲肠壁增厚的脓性物。36 例患者(27%)同时伴有阑尾扩张 8 至 12 毫米。102 例患者仅接受抗生素初始治疗,30 例患者接受腹腔镜治疗,包括部分盲肠切除术(n=8)或阑尾切除术合并憩室切除术(n=9)或单独阑尾切除术(n=13)。我们比较了两组在中位随访 46 个月期间的临床结果。
所有患者均成功接受初始治疗。在仅接受初始抗生素治疗的 102 例患者中,有 6 例(6%)在随访期间复发(3 例在盲肠,3 例在升结肠或横结肠)。其中 5 例患者接受了重复抗生素治疗,1 例因穿孔行回结肠切除术。在接受腹腔镜治疗的 30 例患者中,有 2 例(7%)复发(升结肠),并用抗生素治疗。
疑似单纯性盲肠憩室炎的初始抗生素治疗与腹腔镜治疗在预防复发方面具有相当的疗效。