Kreiner Benedikt, Denzinger Stefan, Ganzer Roman, Fritsche Hans-Martin, Burger Maximilian, Wieland Wolf F, Otto Wolfgang
Department of Urology, University of Regensburg, Germany.
J Med Case Rep. 2010 Oct 12;4:320. doi: 10.1186/1752-1947-4-320.
Primary tumors of seminal vesicles are rare and only a few cases have been reported. Diagnosis is difficult due to the absence of early clinical signs. Prognosis is generally poor.
We present the case of a 70-year-old Caucasian man with a seminal vesicle mass and concomitant lymph node metastasis detected by computed tomography and body positron emission tomography/low-dose computed tomography scan carried out for evaluation of Lambert Eaton syndrome. Transrectal ultrasound-guided biopsy showed a poorly differented neuroendocrine carcinoma with an immunhistochemical profile similar to small cell lung cancer. Following chemotherapy the disease was stable and active surveillance was initiated.
Lambert Eaton syndrome may be the initial symptom of a seminal vesicle mass. Diagnosis needs to be obtained by transrectal biopsy and chemotherapy may delay progression of the tumor.
精囊原发性肿瘤罕见，仅有少数病例报道。由于缺乏早期临床症状，诊断困难。预后通常较差。
我们报告一例70岁白种男性，因评估兰伯特-伊顿综合征行计算机断层扫描及全身正电子发射断层扫描/低剂量计算机断层扫描，发现精囊肿物并伴有淋巴结转移。经直肠超声引导下活检显示为低分化神经内分泌癌，免疫组化特征类似于小细胞肺癌。化疗后病情稳定，开始进行主动监测。
兰伯特-伊顿综合征可能是精囊肿物的首发症状。需经直肠活检确诊，化疗可能延缓肿瘤进展。
