Center for Clinical Innovation, Parkland Health and Hospital System, Dallas, TX 75235, USA.
Med Care. 2010 Nov;48(11):981-8. doi: 10.1097/MLR.0b013e3181ef60d9.
A real-time electronic predictive model that identifies hospitalized heart failure (HF) patients at high risk for readmission or death may be valuable to clinicians and hospitals who care for these patients.
An automated predictive model for 30-day readmission and death was derived and validated from clinical and nonclinical risk factors present on admission in 1372 HF hospitalizations to a major urban hospital between January 2007 and August 2008. Data were extracted from an electronic medical record. The performance of the electronic model was compared with mortality and readmission models developed by the Center for Medicaid and Medicare Services (CMS models) and a HF mortality model derived from the Acute Decompensated Heart Failure Registry (ADHERE model).
The 30-day mortality and readmission rates were 3.1% and 24.1% respectively. The electronic model demonstrated good discrimination for 30 day mortality (C statistic 0.86) and readmission (C statistic 0.72) and performed as well, or better than, the ADHERE model and CMS models for both outcomes (C statistic ranges: 0.72-0.73 and 0.56-0.66 for mortality and readmissions respectively; P < 0.05 in all comparisons). Markers of social instability and lower socioeconomic status improved readmission prediction in the electronic model (C statistic 0.72 vs. 0.61, P < 0.05).
Clinical and social factors available within hours of hospital presentation and extractable from an EMR predicted mortality and readmission at 30 days. Incorporating complex social factors increased the model's accuracy, suggesting that such factors could enhance risk adjustment models designed to compare hospital readmission rates.
对于治疗心力衰竭(HF)患者的临床医生和医院来说,一种能够实时识别再入院或死亡高危患者的电子预测模型可能具有重要价值。
我们从 2007 年 1 月至 2008 年 8 月期间在一家主要城市医院收治的 1372 例 HF 住院患者的入院时临床和非临床风险因素中,推导出并验证了一种用于预测 30 天内再入院和死亡的自动化预测模型。数据从电子病历中提取。我们将电子模型的性能与医疗保险和医疗补助服务中心(CMS 模型)开发的死亡率和再入院模型以及从急性失代偿性心力衰竭登记处(ADHERE 模型)得出的 HF 死亡率模型进行了比较。
30 天死亡率和再入院率分别为 3.1%和 24.1%。该电子模型对 30 天死亡率(C 统计量 0.86)和再入院率(C 统计量 0.72)的区分度较好,在这两个结局方面,其性能与 ADHERE 模型和 CMS 模型相当,或优于这些模型(C 统计量范围:死亡率和再入院率分别为 0.72-0.73 和 0.56-0.66;所有比较 P < 0.05)。社会不稳定和较低社会经济地位的标志物改善了电子模型的再入院预测(C 统计量 0.72 与 0.61 相比,P < 0.05)。
可在患者入院数小时内获得并从电子病历中提取的临床和社会因素可预测 30 天内的死亡率和再入院率。纳入复杂的社会因素可提高模型的准确性,这表明这些因素可增强旨在比较医院再入院率的风险调整模型。