Department of Medicine and Center for Patient Care and Outcomes Research (PCOR), Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.
J Gen Intern Med. 2011 Mar;26(3):280-6. doi: 10.1007/s11606-010-1525-4. Epub 2010 Oct 13.
Blood pressure (BP) control remains elusive for many Americans. Although home health nurses are uniquely positioned to help vulnerable individuals achieve BP control, hypertension (HTN) management has not been a high priority in post-acute care.
To examine the effects of two home-based interventions designed to improve BP outcomes among high-risk African-American patients.
Cluster randomized controlled trial.
A total of 845 newly admitted patients with uncontrolled HTN (JNC7 stages 1 or 2).
The "basic" intervention delivered key HTN information to clinicians and patients, and a home BP monitor to patients, while the patients received usual post-acute care. The "augmented" intervention provided more intensive and extensive HTN information, monitoring and feedback for 3 months beyond the index home care admission.
Primary: BP control. Secondary: reductions in mmHG SBP and DBP, improvements in proportions improving JNC7 stage or achieving clinically meaningful reductions in SBP and DBP.
Multivariate regression models.
The basic intervention produced no significant BP improvements; the augmented intervention significantly improved stage 2 patients' outcomes. Among stage 2 patients, the augmented intervention increased BP control by 8.7 percentage points relative to usual care (8.9% vs. 17.6%; p=0.01), yielded an 8.3 mmHG relative reduction in SBP (p=0.01), and increased the proportion achieving at least a 20 mmHG reduction in SBP by 16.4 percentage points (p=0.01).
Among stage 2 patients, a nurse-led intervention providing additional HTN medication review and patient self-management support during the 3-month post-acute care period yielded significant improvements in 3-month BP control, plus improvements in secondary BP outcomes.
许多美国人的血压(BP)控制仍然难以实现。尽管家庭保健护士在帮助弱势群体实现 BP 控制方面具有独特的优势,但高血压(HTN)管理在康复后护理中并未得到高度重视。
检验两种基于家庭的干预措施对改善高危非裔美国患者 BP 结果的影响。
整群随机对照试验。
共有 845 名新入院的 HTN 控制不佳(JNC7 1 期或 2 期)患者。
“基本”干预向临床医生和患者提供关键的 HTN 信息,并向患者提供家用血压监测仪,而患者接受常规康复后护理。“增强”干预提供了更密集、更广泛的 HTN 信息、监测和反馈,超出了指数家庭护理入院 3 个月。
主要:BP 控制。次要:收缩压和舒张压降低,JNC7 阶段改善或收缩压和舒张压达到临床显著降低的比例提高。
多变量回归模型。
基本干预对 BP 无显著改善;增强干预显著改善了 2 期患者的结果。在 2 期患者中,与常规护理相比,增强干预使 BP 控制增加了 8.7 个百分点(8.9%对 17.6%;p=0.01),收缩压相对降低 8.3mmHg(p=0.01),并使收缩压至少降低 20mmHg 的比例增加了 16.4 个百分点(p=0.01)。
在 2 期患者中,由护士主导的干预措施在康复后护理的 3 个月期间提供了额外的 HTN 药物审查和患者自我管理支持,显著改善了 3 个月的 BP 控制,并改善了次要 BP 结果。