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基于群组的生活方式干预能否延缓 2 型糖尿病的发病?一项随机对照试验。

Can the onset of type 2 diabetes be delayed by a group-based lifestyle intervention? A randomised control trial.

机构信息

Faculty of Life and Social Sciences, Swinburne University of Technology, Melbourne, Australia.

出版信息

Psychol Health. 2011 Apr;26(4):485-99. doi: 10.1080/08870440903548749. Epub 2010 Oct 11.

DOI:10.1080/08870440903548749
PMID:20945253
Abstract

This study was a randomised control trial with a waiting control group. It was designed to evaluate the effectiveness of a 6-month, group-based diabetes prevention programme, The Healthy Living Course and assess whether participation in the programme led to changes in modifiable risk factors for type 2 diabetes among an already at-risk pre-diabetic population. Individuals designated at risk for diabetes by their general practitioners (GPs) were screened using an Oral Glucose Tolerance Test. Volunteers (N = 307) with pre-diabetes were assigned to an intervention or wait-control group in the ratio of approximately 2 : 1. The sample was pre-tested on biochemical, anthropometric and self-report behavioural, cognitive and mood variables and post-tested either at the end of the educational/support-based lifestyle programme or the end of the wait period. The intervention group significantly improved their diabetes knowledge, motivation to change, positive affect, healthy eating and activity levels and showed significantly greater reductions in weight, body mass index, waist circumference, diastolic blood pressure and fasting plasma glucose in comparison with controls. The intervention group also changed their diagnostic status from pre-diabetes to non-diabetes at a greater rate than the wait group (43% vs. 26%) who received standard care from their GPs.

摘要

本研究为一项随机对照试验,设等待对照 组。旨在评估为时 6 个月的团体基础糖尿病预防计 划——健康生活课程的有效性,并评估该计 划是否能改变已经处于糖尿病前期的高危人群中 2 型糖尿病的可改变风险因素。通过口服葡萄糖耐量试 验,由全科医生(GPs)指定处于糖尿病高危人群的个体接受筛查。将有前驱糖尿病的志愿者(N=307)按照大约 2:1 的比例分配到干预组或等待对照组。该样本在生化、人体测量和自我报告的行为、认知和情绪变量方面进行了预测试,并在教育/基于支持的生活方式方案结束时或等待期结束时进行了后测试。与对照组相比,干预组的糖尿病知识、改变动机、积极情绪、健康饮食和活动水平显著提高,体重、体重指数、腰围、舒张压和空腹血糖显著降低。与仅接受其 GP 标准护理的对照组(43%比 26%)相比,干预组将其诊断状态从前驱糖尿病转变为非糖尿病的比例更高。

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