Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh.
Trop Med Int Health. 2010 Nov;15(11):1382-9. doi: 10.1111/j.1365-3156.2010.02635.x. Epub 2010 Oct 13.
To analyse the feasibility, acceptability and effectiveness of insecticide-treated bed nets with slow-release insecticides (KO Tab 123) as an option for kala-azar vector management in Bangladesh.
Intervention study involving an insecticide dipping programme through village health workers supervised by public health officers covering 6967 households in Mymensingh and 8287 in Rajshahi district. In a subsample of households, sandfly densities at baseline, 1, 12 and 18 months were measured with CDC light traps both in intervention and control areas. Bioassays were performed for determining the bioavailability of the insecticide and tests of chemical residues in the treated bed nets were undertaken. Satisfaction surveys and direct observation of use of treated bed net use were conducted.
The dipping programme was feasible with the help of communities and public health staff, was well accepted, reached a coverage of 98.2% and 96.2% in the two study sites within 4 weeks and was effective in terms of a significant reduction in sandfly densities (approximately 60%) for a period of 18 months. Bioassay results were satisfactory (>80% sandfly mortality) and the average chemical content of the treated bed nets was sufficient for killing sand flies at the end of the observation period.
Bed nets treated with slow-release insecticides can be an important complementary measure for sandfly control in the visceral leishmaniasis elimination programme.
分析作为孟加拉国内脏利什曼病消除规划中控制白蛉媒介的一种选择，使用缓效杀虫剂处理的防虫蚊帐（KO Tab 123）的可行性、可接受性和效果。
这是一项干预研究，通过乡村卫生工作者实施杀虫剂浸渍方案，由公共卫生官员监督，覆盖了迈门辛和拉杰沙希地区的 6967 户和 8287 户家庭。在家庭的一个子样本中，在干预区和对照区使用 CDC 诱捕器测量了基线、1 个月、12 个月和 18 个月时的白蛉密度。进行了生物测定以确定杀虫剂的生物利用度，并对处理过的蚊帐中的化学残留物进行了测试。进行了满意度调查和对使用处理过的蚊帐的直接观察。
在社区和公共卫生工作人员的帮助下，浸渍方案是可行的，得到了很好的接受，在两个研究地点的覆盖范围在 4 周内达到了 98.2%和 96.2%，并且在 18 个月的时间内显著降低了白蛉密度（约 60%），效果显著。生物测定结果令人满意（>80%的白蛉死亡率），处理过的蚊帐的平均化学含量在观察期结束时足以杀死白蛉。
使用缓效杀虫剂处理的蚊帐可以成为内脏利什曼病消除规划中控制白蛉的一项重要补充措施。
