用于抗耐药菌的新型抗生素。
New antibiotics for antibiotic-resistant bacteria.
作者信息
Stubbings William, Labischinski Harald
机构信息
MerLion Pharmaceuticals GmbH Robert-Röessle Str-10, D-13125 Berlin Germany.
出版信息
F1000 Biol Rep. 2009 May 28;1:40. doi: 10.3410/B1-40.
Abstract
The need for new antibiotics to effectively treat antibiotic-resistant infections remains unfulfilled. Despite the well-publicised concern over this issue, only two novel antibiotic classes have been introduced in the past 20 years alongside several new agents of existing classes. Accordingly, the current antibiotic armoury remains inadequate to meet the challenges posed by resistance today. More worryingly, there are very few new agents being developed that can be expected to replace existing antibiotics that succumb to the rising tide of resistance.
摘要
有效治疗抗生素耐药性感染所需的新型抗生素仍未得到满足。尽管对这个问题已经有了广泛的关注，但在过去20年里，仅引入了两类新型抗生素以及几种现有类别的新药物。因此，目前的抗生素库仍然不足以应对当今耐药性带来的挑战。更令人担忧的是，正在研发的有望取代因耐药性不断上升而失效的现有抗生素的新药极少。
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