Shav-Tal Yaron, Gruenbaum Yosef
The Mina and Everard Goodman Faculty of Life Sciences and Institute of Nanotechnology, Bar-Ilan University, Ramat Gan 52900, Israel.
F1000 Biol Rep. 2009 Apr 29;1:29. doi: 10.3410/B1-29.
In eukaryotes, mRNA molecules are transcribed from nuclear DNA and commute through a labyrinth of nucleoplasmic passageways to the nuclear envelope where they are exported to the cytoplasm. New findings provide tools and insights into the biophysical properties that govern mRNA translocations en route to the cytoplasm and suggest that mRNA molecules move in a discontinuous manner due to transient interactions with the nuclear environment.
在真核生物中，信使核糖核酸（mRNA）分子从核DNA转录而来，通过核质通道的迷宫到达核膜，然后被输出到细胞质中。新的研究结果提供了工具，并深入了解了控制mRNA向细胞质转运的生物物理特性，表明mRNA分子由于与核环境的短暂相互作用而以不连续的方式移动。
