Guy's and St. Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.
Mod Rheumatol. 2011 Apr;21(2):211-4. doi: 10.1007/s10165-010-0364-9. Epub 2010 Oct 15.
We describe the case of a 79-year-old lady who developed pulmonary emboli on a background of active Wegener's granulomatosis (WG). The literature reports an increased association of venous thromboembolic disease and the small vessel vasculitides, including WG. This case report explores the issues surrounding systemic anticoagulation in the context of a systemic vasculitis that predisposes to severe bleeding, in particular from the respiratory tract.
我们描述了一例 79 岁女性病例,该患者在患有活动性韦格纳肉芽肿(WG)的背景下发生了肺栓塞。文献报道静脉血栓栓塞性疾病与包括 WG 在内的小血管血管炎之间的关联增加。本病例报告探讨了在易发生严重出血(特别是来自呼吸道)的全身性血管炎的情况下,全身性抗凝治疗相关的问题。