Save Sight Institute, Sydney Eye Hospital, Australia.
Clin Exp Ophthalmol. 2010 Jan;38(1):65-7. doi: 10.1111/j.1442-9071.2009.02217.x.
We present a case of Wegener's granulomatosis (WG) in a 79-year-old man with limbitis and granulomatous conjunctivitis, on a background of polymyalgia rheumatica (PMR). The undifferentiated nature of ocular presentations of WG can be diagnostically challenging, especially in cases, such as this, where findings are initially inconclusive and evolve with time. This case highlights the significance of a history of PMR in patients with ocular inflammation. The systemic inflammatory systems of WG, including arthralgias, may mimic other conditions such as PMR. Patients with undifferentiated ocular inflammatory syndromes should be questioned regarding arthralgias, myalgias and stiffness. Such symptoms, or a background of PMR, should raise suspicion of WG.
我们报告了一例 79 岁男性患者,他患有韦格纳肉芽肿(WG),表现为眼睑缘炎和肉芽肿性结膜炎,同时患有巨细胞动脉炎(PMR)。WG 的眼部表现具有非特异性,这在诊断上具有挑战性,特别是在这种情况下,最初的检查结果不确定,并且随着时间的推移而变化。本病例强调了有眼部炎症的 PMR 病史的重要性。WG 的全身性炎症系统,包括关节痛,可能会模仿其他疾病,如 PMR。对于具有未分化眼部炎症综合征的患者,应询问其关节痛、肌痛和僵硬情况。这些症状或 PMR 病史应提示WG 的可能性。