基于表面等离子体共振的生物传感器仪器设计的新趋势。
New trends in instrumental design for surface plasmon resonance-based biosensors.
机构信息
Department of Chemistry, University of California, Riverside, CA 92521, USA.
出版信息
Biosens Bioelectron. 2011 Jan 15;26(5):1815-24. doi: 10.1016/j.bios.2010.09.030. Epub 2010 Sep 22.
Abstract
Surface plasmon resonance (SPR)-based biosensing is one of the most advanced label free, real time detection technologies. Numerous research groups with divergent scientific backgrounds have investigated the application of SPR biosensors and studied the fundamental aspects of surface plasmon polaritons that led to new, related instrumentation. As a result, this field continues to be at the forefront of evolving sensing technology. This review emphasizes the new developments in the field of SPR-related instrumentation including optical platforms, chips design, nanoscale approach and new materials. The current tendencies in SPR-based biosensing are identified and the future direction of SPR biosensor technology is broadly discussed.
摘要
基于表面等离子体共振（SPR）的生物传感是最先进的无标记、实时检测技术之一。许多具有不同科学背景的研究小组研究了 SPR 生物传感器的应用，并研究了导致新的相关仪器的表面等离子体激元的基本方面。因此，该领域继续处于不断发展的传感技术的前沿。本文综述了与 SPR 相关的仪器领域的新进展，包括光学平台、芯片设计、纳米级方法和新材料。确定了基于 SPR 的生物传感的当前趋势，并广泛讨论了 SPR 生物传感器技术的未来方向。
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