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pR3521 序列，一种来自大肠杆菌的 IncB 质粒，编码 ACC-4、SCO-1 和 TEM-1β-内酰胺酶。

Sequence of pR3521, an IncB plasmid from Escherichia coli encoding ACC-4, SCO-1, and TEM-1 beta-lactamases.

机构信息

Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.

出版信息

Antimicrob Agents Chemother. 2011 Jan;55(1):376-81. doi: 10.1128/AAC.00875-10. Epub 2010 Oct 18.

DOI:10.1128/AAC.00875-10
PMID:20956594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3019680/
Abstract

The sequence of pR3521, a self-transmissible plasmid from Escherichia coli, was determined. pR3521 (110,416 bp) comprised a contiguous IncB sequence (84,034 bp) sharing extensive similarities with IncI replicons and an acquired region (26,382 bp) carrying sequences of diverse origin, containing bla(ACC-4), bla(SCO-1), bla(TEM-1b) (two copies), strA, strB, sul2, and aacC2.

摘要

pR3521 源自大肠杆菌，为可自主转移的质粒，其序列已被确定。pR3521 （110416bp）包含连续的 IncB 序列（84034bp），与 IncI 复制子有广泛的相似性，以及一个获得性区域（26382bp），携带多种来源的序列，包括 bla(ACC-4)、bla(SCO-1)、bla(TEM-1b)（两个拷贝）、strA、strB、sul2 和 aacC2。

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2
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Microb Drug Resist. 2009 Dec;15(4):279-86. doi: 10.1089/mdr.2009.0035.
3
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Antimicrob Agents Chemother. 2009 Oct;53(10):4472-82. doi: 10.1128/AAC.00688-09. Epub 2009 Aug 17.
4
Resistance plasmid families in Enterobacteriaceae.肠杆菌科中的耐药性质粒家族。
Antimicrob Agents Chemother. 2009 Jun;53(6):2227-38. doi: 10.1128/AAC.01707-08. Epub 2009 Mar 23.
5
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Antimicrob Agents Chemother. 2009 Mar;53(3):1088-93. doi: 10.1128/AAC.00800-08. Epub 2008 Dec 15.
6
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