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pR3521 序列,一种来自大肠杆菌的 IncB 质粒,编码 ACC-4、SCO-1 和 TEM-1β-内酰胺酶。

Sequence of pR3521, an IncB plasmid from Escherichia coli encoding ACC-4, SCO-1, and TEM-1 beta-lactamases.

机构信息

Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.

出版信息

Antimicrob Agents Chemother. 2011 Jan;55(1):376-81. doi: 10.1128/AAC.00875-10. Epub 2010 Oct 18.

Abstract

The sequence of pR3521, a self-transmissible plasmid from Escherichia coli, was determined. pR3521 (110,416 bp) comprised a contiguous IncB sequence (84,034 bp) sharing extensive similarities with IncI replicons and an acquired region (26,382 bp) carrying sequences of diverse origin, containing bla(ACC-4), bla(SCO-1), bla(TEM-1b) (two copies), strA, strB, sul2, and aacC2.

摘要

pR3521 源自大肠杆菌,为可自主转移的质粒,其序列已被确定。pR3521 (110416bp)包含连续的 IncB 序列(84034bp),与 IncI 复制子有广泛的相似性,以及一个获得性区域(26382bp),携带多种来源的序列,包括 bla(ACC-4)、bla(SCO-1)、bla(TEM-1b)(两个拷贝)、strA、strB、sul2 和 aacC2。

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