• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Reduced Susceptibility to Carbapenems in a Klebsiella pneumoniae Clinical Isolate Producing SCO-1 and CTX-M-15 β-Lactamases Together with OmpK35 and OmpK36 Porin Deficiency.

作者信息

Venditti Carolina, Butera Ornella, Proia Anna, Rigacci Luigi, Mariani Bruno, Parisi Gabriella, Messina Francesco, Capone Alessandro, Nisii Carla, Di Caro Antonino

机构信息

Laboratory of Microbiology, National Institute for Infectious Diseases L. Spallanzani, IRCCS, Rome, Italy.

Haematology and Haematopoietic Stem Cells Transplant Unit, San Camillo-Forlanini Hospital, Rome, Italy.

出版信息

Antimicrob Agents Chemother. 2020 Jul 22;64(8). doi: 10.1128/AAC.00556-20.

DOI:10.1128/AAC.00556-20
PMID:32423955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7526818/
Abstract
摘要

相似文献

1
Reduced Susceptibility to Carbapenems in a Klebsiella pneumoniae Clinical Isolate Producing SCO-1 and CTX-M-15 β-Lactamases Together with OmpK35 and OmpK36 Porin Deficiency.一株同时产SCO-1和CTX-M-15β-内酰胺酶并伴有外膜孔蛋白OmpK35和OmpK36缺失的肺炎克雷伯菌临床分离株对碳青霉烯类药物敏感性降低
Antimicrob Agents Chemother. 2020 Jul 22;64(8). doi: 10.1128/AAC.00556-20.
2
Role of association of OmpK35 and OmpK36 alteration and bla and/or bla genes in conferring carbapenem resistance among non-carbapenemase-producing Klebsiella pneumoniae.OmpK35 和 OmpK36 改变与 bla 和/或 bla 基因的关联在非碳青霉烯酶产生肺炎克雷伯菌中赋予碳青霉烯类耐药的作用。
Int J Antimicrob Agents. 2018 Dec;52(6):898-905. doi: 10.1016/j.ijantimicag.2018.03.020. Epub 2018 Apr 2.
3
Mutation of Causes OmpK35 and OmpK36 Porin Downregulation and Reduced Meropenem-Vaborbactam Susceptibility in KPC-Producing Klebsiella pneumoniae.产 KPC 肺炎克雷伯菌中 突变导致 OmpK35 和 OmpK36 孔蛋白下调和美罗培南-沃诺拉赞药敏性降低。
Antimicrob Agents Chemother. 2020 Jun 23;64(7). doi: 10.1128/AAC.02208-19.
4
Global survey of Klebsiella pneumoniae major porins from ertapenem non-susceptible isolates lacking carbapenemases.对缺乏碳青霉烯酶的厄他培南不敏感肺炎克雷伯菌主要孔蛋白的全球调查。
J Med Microbiol. 2018 Mar;67(3):289-295. doi: 10.1099/jmm.0.000691. Epub 2018 Feb 5.
5
Reduced susceptibility to carbapenems in Klebsiella pneumoniae clinical isolates associated with plasmid-mediated beta-lactamase production and OmpK36 porin deficiency.肺炎克雷伯菌临床分离株对碳青霉烯类药物敏感性降低，与质粒介导的β-内酰胺酶产生及外膜孔蛋白OmpK36缺失有关。
J Med Microbiol. 2009 Sep;58(Pt 9):1196-1202. doi: 10.1099/jmm.0.008094-0. Epub 2009 Jun 15.
6
The Role of OmpK35, OmpK36 Porins, and Production of β-Lactamases on Imipenem Susceptibility in Klebsiella pneumoniae Clinical Isolates, Cairo, Egypt.埃及开罗肺炎克雷伯菌临床分离株中OmpK35、OmpK36孔蛋白及β-内酰胺酶产生对亚胺培南敏感性的作用
Microb Drug Resist. 2015 Dec;21(6):577-80. doi: 10.1089/mdr.2014.0226. Epub 2015 May 6.
7
OmpK26, a novel porin associated with carbapenem resistance in Klebsiella pneumoniae.OmpK26，一种与肺炎克雷伯菌碳青霉烯类耐药相关的新型孔蛋白。
Antimicrob Agents Chemother. 2011 Oct;55(10):4742-7. doi: 10.1128/AAC.00309-11. Epub 2011 Aug 1.
8
An Outbreak of NDM-1-Producing Klebsiella pneumoniae, Associated with OmpK35 and OmpK36 Porin Loss in Tunisia.突尼斯产NDM-1肺炎克雷伯菌的暴发，与外膜孔蛋白OmpK35和OmpK36缺失有关。
Microb Drug Resist. 2018 Oct;24(8):1137-1147. doi: 10.1089/mdr.2017.0165. Epub 2018 Jan 26.
9
Characterization of the Genetic Background of KPC-2-Producing with Insertion Elements Disrupting the Porin Gene.产 KPC-2 酶 与插入元件破坏孔蛋白基因 的遗传背景特征。
Microb Drug Resist. 2020 Sep;26(9):1050-1057. doi: 10.1089/mdr.2019.0410. Epub 2020 Apr 13.
10
Carbapenem Resistance Caused by High-Level Expression of OXA-663 β-Lactamase in an OmpK36-Deficient Klebsiella pneumoniae Clinical Isolate.高产 OXA-663β-内酰胺酶导致 OmpK36 缺陷型肺炎克雷伯菌临床分离株碳青霉烯类耐药。
Antimicrob Agents Chemother. 2018 Oct 24;62(11). doi: 10.1128/AAC.01281-18. Print 2018 Nov.

引用本文的文献

1
Detection of rare β-lactamase from a high-risk clone in Peru.在秘鲁检测来自高风险克隆株的罕见β-内酰胺酶
JAC Antimicrob Resist. 2025 May 26;7(3):dlaf089. doi: 10.1093/jacamr/dlaf089. eCollection 2025 Jun.
2
Comparative Genomics Reveals Novel Species and Insights into the Biotechnological Potential, Virulence, and Resistance of .比较基因组学揭示了新物种以及对……的生物技术潜力、毒力和抗性的见解。
Genes (Basel). 2023 Sep 10;14(9):1783. doi: 10.3390/genes14091783.
3
First Belgian Report of Ertapenem Resistance in an ST11 Strain Isolated from a Dog Carrying and Combined with Permeability Defects.比利时首例关于从携带并伴有通透性缺陷的犬类中分离出的ST11菌株对厄他培南耐药的报告。
Antibiotics (Basel). 2022 Sep 15;11(9):1253. doi: 10.3390/antibiotics11091253.
4
Epidemiology and Genomic Characteristics of Bloodstream Infection Caused by Carbapenem-Resistant With Decreased Susceptibility to Aztreonam/Avibactam in China.中国耐碳青霉烯类抗生素/阿维巴坦类药物敏感性降低的血流感染的流行病学和基因组特征。
Front Cell Infect Microbiol. 2022 Jun 22;12:926209. doi: 10.3389/fcimb.2022.926209. eCollection 2022.
5
Survey on Carbapenem-Resistant Bacteria in Pigs at Slaughter and Comparison with Human Clinical Isolates in Italy.意大利屠宰猪中耐碳青霉烯类细菌的调查及其与人类临床分离株的比较
Antibiotics (Basel). 2022 Jun 7;11(6):777. doi: 10.3390/antibiotics11060777.
6
Microbial Resistance to Antibiotics and Effective Antibiotherapy.微生物对抗生素的耐药性与有效的抗生素治疗
Biomedicines. 2022 May 12;10(5):1121. doi: 10.3390/biomedicines10051121.
7
Importance of Surveillance of New Delhi Metallo-Beta-Lactamase : Molecular Characterization and Clonality of Strains Isolated in the Lazio Region, Italy.新德里金属β-内酰胺酶监测的重要性：意大利拉齐奥地区分离菌株的分子特征与克隆性
Infect Drug Resist. 2021 Sep 8;14:3659-3665. doi: 10.2147/IDR.S318717. eCollection 2021.

本文引用的文献

1
Role of association of OmpK35 and OmpK36 alteration and bla and/or bla genes in conferring carbapenem resistance among non-carbapenemase-producing Klebsiella pneumoniae.OmpK35 和 OmpK36 改变与 bla 和/或 bla 基因的关联在非碳青霉烯酶产生肺炎克雷伯菌中赋予碳青霉烯类耐药的作用。
Int J Antimicrob Agents. 2018 Dec;52(6):898-905. doi: 10.1016/j.ijantimicag.2018.03.020. Epub 2018 Apr 2.
2
Global survey of Klebsiella pneumoniae major porins from ertapenem non-susceptible isolates lacking carbapenemases.对缺乏碳青霉烯酶的厄他培南不敏感肺炎克雷伯菌主要孔蛋白的全球调查。
J Med Microbiol. 2018 Mar;67(3):289-295. doi: 10.1099/jmm.0.000691. Epub 2018 Feb 5.
3
Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis.发现、研究和开发新抗生素：世界卫生组织抗微生物药物耐药性和结核病优先病原体清单。
Lancet Infect Dis. 2018 Mar;18(3):318-327. doi: 10.1016/S1473-3099(17)30753-3. Epub 2017 Dec 21.
4
Evolving beta-lactamase epidemiology in Enterobacteriaceae from Italian nationwide surveillance, October 2013: KPC-carbapenemase spreading among outpatients.2013年10月意大利全国监测中肠杆菌科细菌β-内酰胺酶流行病学的演变：KPC碳青霉烯酶在门诊患者中的传播。
Euro Surveill. 2017 Aug 3;22(31). doi: 10.2807/1560-7917.ES.2017.22.31.30583.
5
New plasmid-mediated aminoglycoside 6'-N-acetyltransferase, AAC(6')-Ian, and ESBL, TLA-3, from a Serratia marcescens clinical isolate.来自粘质沙雷氏菌临床分离株的新型质粒介导的氨基糖苷6'-N-乙酰基转移酶AAC(6')-Ian和超广谱β-内酰胺酶TLA-3
J Antimicrob Chemother. 2015 May;70(5):1331-7. doi: 10.1093/jac/dku537. Epub 2015 Jan 8.
6
In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing.使用质粒查找工具（PlasmidFinder）和质粒多位点序列分型进行质粒的电子检测和分型
Antimicrob Agents Chemother. 2014 Jul;58(7):3895-903. doi: 10.1128/AAC.02412-14. Epub 2014 Apr 28.
7
Complete sequencing of an IncH plasmid carrying the blaNDM-1, blaCTX-M-15 and qnrB1 genes.携带blaNDM-1、blaCTX-M-15和qnrB1基因的IncH质粒的全序列测定。
J Antimicrob Chemother. 2012 Jul;67(7):1645-50. doi: 10.1093/jac/dks114. Epub 2012 Apr 17.
8
Sequence of pR3521, an IncB plasmid from Escherichia coli encoding ACC-4, SCO-1, and TEM-1 beta-lactamases.pR3521 序列，一种来自大肠杆菌的 IncB 质粒，编码 ACC-4、SCO-1 和 TEM-1β-内酰胺酶。
Antimicrob Agents Chemother. 2011 Jan;55(1):376-81. doi: 10.1128/AAC.00875-10. Epub 2010 Oct 18.
9
An ertapenem-resistant extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae clone carries a novel OmpK36 porin variant.产厄他培南耐药超广谱β-内酰胺酶的肺炎克雷伯菌克隆携带一种新型的 OmpK36 孔蛋白变体。
Antimicrob Agents Chemother. 2010 Oct;54(10):4178-84. doi: 10.1128/AAC.01301-09. Epub 2010 Jul 26.
10
Molecular epidemiology and genetic environment of acquired bla ACC-1 in Salmonella enterica serotype Livingstone causing a large nosocomial outbreak in Tunisia.肠沙门氏菌血清型利文斯顿中获得性 bla ACC-1 的分子流行病学和遗传环境导致突尼斯发生大规模医院感染暴发。
Microb Drug Resist. 2009 Dec;15(4):279-86. doi: 10.1089/mdr.2009.0035.