School of Engineering and Applied Sciences and Department of Physics, Harvard University, Cambridge, MA 02138, USA.
Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19163-6. doi: 10.1073/pnas.1006888107. Epub 2010 Oct 20.
Adding reagents to drops is one of the most important functions in droplet-based microfluidic systems; however, a robust technique to accomplish this does not exist. Here, we introduce the picoinjector, a robust device to add controlled volumes of reagent using electro-microfluidics at kilohertz rates. It can also perform multiple injections for serial and combinatorial additions.
在液滴微流控系统中,向液滴中添加试剂是最重要的功能之一;然而,目前还没有一种稳健的技术可以实现这一功能。在这里,我们介绍了皮升注射器,这是一种使用电微流控技术以千赫兹速率添加受控体积试剂的稳健设备。它还可以进行多次注射,用于连续和组合添加。