University of Maryland School of Medicine, Baltimore, MD, USA.
J Dermatolog Treat. 2012 Feb;23(1):52-6. doi: 10.3109/09546634.2010.495381. Epub 2010 Oct 22.
Disseminated superficial actinic porokeratosis (DSAP) is a chronic disorder of keratinization characterized by numerous papules and plaques distributed over sun-exposed sites. Treatments are poorly standardized and several investigational therapies have demonstrated limited success in treating DSAP. To our knowledge, there have been no systematic reviews of the literature regarding the treatment of this disease. Herein, we review recent studies pertaining to the treatment of DSAP and evaluate the level of evidence for each of these therapeutic modalities.
播散性浅表性光线性汗孔角化症(DSAP)是一种慢性角化异常性疾病,其特征为大量丘疹和斑块,分布于暴露于阳光的部位。目前的治疗方法尚未标准化,并且几种研究性疗法在治疗 DSAP 方面仅取得了有限的成功。据我们所知,目前尚无针对该疾病治疗的系统评价文献。在此,我们回顾了最近有关 DSAP 治疗的研究,并评估了每种治疗方式的证据水平。