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法国2009年甲型H1N1流感大流行疫苗接种情况:哪些人愿意接种疫苗以及原因是什么?

The 2009 pandemic H1N1 influenza vaccination in France: who accepted to receive the vaccine and why?

作者信息

Raude Jocelyn, Caille-Brillet Anne-Laure, Setbon Michel

机构信息

EHESP School of Public Health, Rennes - Sorbonne Paris Cité, France and EHESP, Rennes-Sorbonne Paris Cité

出版信息

PLoS Curr. 2010 Oct 19;2:RRN1188. doi: 10.1371/currents.RRN1188.

Abstract

INTRODUCTION

Previous studies investigating determinants of 2009 (H1N1) pandemic influenza vaccine acceptance have focused on target groups such as healthcare workers. Few studies in the European Union have examined the self-reported reasons as well as predictive socio-demographic and health factors for pandemic influenza vaccine acceptance in the general population, even though influenza vaccine was recommended for all people.

METHODS

A nationwide telephone survey was conducted in France during the peak of the outbreak that occurred in December 2009 in adults (≥ 16 years), using a proportional random-digit dialing.

RESULTS

Interviews were completed by 1003 individuals, of whom 275 (27.4%) either had received pandemic influenza vaccine during the last weeks or intended to get vaccinated in the next weeks. Acceptance rates of pandemic vaccine were significantly higher among men, more educated and wealthier people, as well as persons who had a prior experience of influenza vaccination. The patterns of self-reported reasons for vaccine acceptance could be broadly divided into 3 groups related to (1) the mental representation of the threat - in particular the beliefs associated with the severity and personal vulnerability to the illness, (2) the perception of efficacy and safety of the vaccine, and (3) trust/distrust toward those advocating the vaccine.

CONCLUSIONS

This national study indicates that social and cognitive determinants of pandemic influenza vaccine acceptance among French adults were relatively similar to those identified by previous studies of acceptance of seasonal influenza vaccine.

摘要

引言

以往关于2009年甲型H1N1流感大流行疫苗接种决定因素的研究主要集中在医护人员等目标群体上。尽管流感疫苗被推荐给所有人,但在欧盟很少有研究调查普通人群接受大流行流感疫苗接种的自我报告原因以及预测性的社会人口统计学和健康因素。

方法

2009年12月法国爆发疫情高峰期,采用按比例随机数字拨号法,对16岁及以上成年人进行了全国性电话调查。

结果

1003人完成了访谈,其中275人(27.4%)在过去几周内接种了大流行流感疫苗或打算在接下来几周内接种。男性、受教育程度更高、更富裕的人群以及有流感疫苗接种史的人群,大流行疫苗接种率显著更高。自我报告的疫苗接种接受原因模式大致可分为3组,分别与(1)对威胁的心理认知——特别是与疾病严重程度和个人易感性相关的信念,(2)对疫苗效力和安全性的认知,以及(3)对倡导疫苗接种者的信任/不信任有关。

结论

这项全国性研究表明,法国成年人接受大流行流感疫苗接种的社会和认知决定因素与先前关于季节性流感疫苗接种接受情况的研究中所确定的因素相对相似。

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