University of Copenhagen, Denmark.
Cephalalgia. 2011 Jan;31(1):43-64. doi: 10.1177/0333102410373159. Epub 2010 Jun 2.
The aim of this study was to determine sex specific co-morbidity of migraine and its subtypes migraine without aura (MO) and migraine with aura (MA) with a number of common somatic diseases.
In 2002, a questionnaire containing previously validated questions to diagnose migraine and its subtypes as well as questions regarding some somatic diseases was sent to 46,418 twins residing in Denmark and born between 1931 and 1982. The twins are representative of the whole Danish population and were used as such in the present study.
We found that 21, 23 and 12 conditions were co-morbid with migraine, MA and MO, respectively. Co-morbid diseases included previously documented diseases: asthma, epilepsy and stroke as well as new conditions: kidney stone, psoriasis, rheumatoid arthritis and fibromyalgia. MA had more co-morbidities than MO and females more than males.
Migraine occurs in 20-30% of several medical conditions. It should be diagnosed and treated along with the primary disease.
本研究旨在确定偏头痛及其亚型（无先兆偏头痛和有先兆偏头痛）与多种常见躯体疾病的性别特异性共病情况。
2002 年，我们向居住在丹麦、1931 年至 1982 年间出生的 46418 对双胞胎寄去了一份问卷，其中包含了之前经过验证的偏头痛及其亚型诊断问题以及一些躯体疾病问题。这些双胞胎代表了整个丹麦人口，我们在本研究中也是将他们作为整体来使用的。
我们发现偏头痛、有先兆偏头痛和无先兆偏头痛分别与 21、23 和 12 种疾病存在共病情况。共病疾病包括之前有记录的疾病：哮喘、癫痫和中风，以及新的疾病：肾结石、银屑病、类风湿关节炎和纤维肌痛。有先兆偏头痛的共病情况比无先兆偏头痛多，女性比男性多。
偏头痛在 20-30%的几种疾病中发生。偏头痛应与基础疾病一起诊断和治疗。
