Department of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Parkinsons Dis. 2010 Jun 30;2010:760196. doi: 10.4061/2010/760196.
Quantification of neuromotor symptoms with device-based measures provides a useful supplement to clinical evaluation. Research using the CATSYS has established its utility as a computerized measurement system to quantify neuromotor function. The primary objective of this study is to provide technical guidance on the use of the CATSYS in Parkinson's disease (PD). Forty-four patients with idiopathic PD and 28 healthy controls were prospectively recruited and evaluated with CATSYS, a portable, Windows-based system consisting of a data logger and four different sensors (tremor pen, touch recording plate, reaction time handle, and force plate for balance recording) for quantification of neuromotor functions. CATSYS discriminated between PD and controls on measurements of rest/postural tremor, pronation/supination, finger tapping, simple reaction time, and postural sway intensity and velocity. CATSYS measurements using the proposed test battery were associated with relevant clinician-rated Unified Parkinson's disease rating scale (UPDRS) items assessing tremor and bradykinesia. More work is warranted to establish CATSYS as a diagnostic/monitoring instrument in movement disorders using the proposed technical approaches.
使用基于设备的测量方法对神经运动症状进行量化为临床评估提供了有用的补充。使用 CATSYS 进行的研究已经证明了其作为一种量化神经运动功能的计算机化测量系统的效用。本研究的主要目的是提供使用 CATSYS 进行帕金森病（PD）的技术指导。前瞻性招募了 44 名特发性 PD 患者和 28 名健康对照者，并使用 CATSYS 进行评估。CATSYS 是一种便携式、基于 Windows 的系统，由数据记录器和四个不同的传感器（震颤笔、触摸记录板、反应时间手柄和用于平衡记录的力板）组成，用于量化神经运动功能。CATSYS 可区分 PD 患者和对照组在静止/姿势性震颤、旋前/旋后、手指敲击、简单反应时间以及姿势摆动强度和速度方面的测量值。使用建议的测试电池进行的 CATSYS 测量与评估震颤和运动迟缓的相关临床医生评定的统一帕金森病评定量表（UPDRS）项目相关。需要进一步的工作来使用建议的技术方法将 CATSYS 确立为运动障碍的诊断/监测工具。
