Sanz M, Newman M G, Nachnani S, Holt R, Stewart R, Flemmig T
UCLA School of Dentistry, Los Angeles, California.
Int J Oral Maxillofac Implants. 1990 Fall;5(3):247-53.
The microbiota associated with oral endosteal sapphire ceramic implants was studied using cultural methods. Samples were taken from both implant and control (tooth) sites, and comparisons were made between healthy and diseased and between implant and control sites. Diseased sites harbored a microbiota with a large number and proportion of Gram-negative anaerobic rods, black-pigmented Bacteroides, and surface translocating bacteria. Healthy sites in the same patients had smaller amounts of bacteria dominated by facultative Gram-positive cocci and rods. The microbiota in diseased and healthy implant and control sites was very similar. It is suggested that peri-implant tissues behave very similarly to periodontal tissues and that peri-implantitis lesions should be considered as site-specific infections harboring a high number of periodontal pathogens, mainly Gram-negative anaerobic rods.
采用培养方法研究了与口腔骨内蓝宝石陶瓷种植体相关的微生物群。从种植体部位和对照（牙齿）部位采集样本，并对健康与患病情况以及种植体与对照部位进行了比较。患病部位的微生物群中革兰氏阴性厌氧杆菌、产黑色素拟杆菌和表面迁移菌的数量及比例较大。同一患者的健康部位细菌数量较少，以兼性革兰氏阳性球菌和杆菌为主。患病和健康的种植体及对照部位的微生物群非常相似。研究表明，种植体周围组织的行为与牙周组织非常相似，种植体周炎病变应被视为特定部位感染，其中含有大量牙周病原体，主要是革兰氏阴性厌氧杆菌。
