Qiao Y F, Wang S X, Wu L J, Li X, Zhu T R
Department of National Products, Shenyang College of Pharmacy.
Yao Xue Xue Bao. 1990;25(11):834-9.
Twelve compounds were isolated from the roots of Rubia cordifolia L.. Nine of them were established by chemical and spectroscopic methods to be alizarin (I),1-hydroxy-2-methyl-9,10-anthraquinone(II),1,3,6-trihydroxy-2-methyl- 9,10-anthra-quinone-3-O-(6'-O-acetyl)-alpha-L-rhamnosyl(1--- -2)-beta-D- glucoside(III),1,3,6-trihydroxy-2-methyl-9,10-anthraqueinone-3-O-a lpha- L-rhamnosyl(1----2)-beta-D-glucoside(IV),1,3,6-trihydrozy-2- methyl-9,10- anthraquinone-3-O-(6'-O-acetyl)-beta-D-glucoside(V),2-carbomethyoxy++ +-3-prenyl- 1,4-naphthohydroquinone di-beta-D-glucoside(VI),rubimallin(VII),beta- sitosterol(VIII) and daucosterol(IX), among them, V is a nwe compound and IX was obtained from this genus for the first time, III, VI and VII showed certain antibacterial activities.
从茜草(Rubia cordifolia L.)根部分离出12种化合物。其中9种通过化学和光谱方法鉴定为茜素(I)、1-羟基-2-甲基-9,10-蒽醌(II)、1,3,6-三羟基-2-甲基-9,10-蒽醌-3-O-(6'-O-乙酰基)-α-L-鼠李糖基(1→2)-β-D-葡萄糖苷(III)、1,3,6-三羟基-2-甲基-9,10-蒽醌-3-O-α-L-鼠李糖基(1→2)-β-D-葡萄糖苷(IV)、1,3,6-三羟基-2-甲基-9,10-蒽醌-3-O-(6'-O-乙酰基)-β-D-葡萄糖苷(V)、2-甲氧羰基-3-异戊烯基-1,4-萘氢醌二-β-D-葡萄糖苷(VI)、红紫素(VII)、β-谷甾醇(VIII)和胡萝卜苷(IX)。其中,V是新化合物,IX首次从该属植物中获得,III、VI和VII表现出一定的抗菌活性。